Douglas J. Rhee, MD

94A. AGENTS FOR RELIEF OF SEASONAL ALLERGIC CONJUNCTIVITIS /OCULAR DISCOMFORTDrug Trade Preparation Usual Dose Notesazelastine Optivar Soln, 0.05% BID H1-antagonist with mast cell stabilizationcromolyn sodium Crolom, Opticrom Soln, 4% QID–Q4 hr Mast cell stabilizer; may take weeks for effectemedastine difumarate Emadine Soln, 0.05% QD-QID H1-antagonistepinastine Elestat Soln, 0.05% BID H1-, H2-antagonist, mast cell inhibitorketotifen fumarate Zaditor Soln, 0.025% BID-TID H1-antagonist, Mast cell stabilizer, Eosinphil inhibitorketorolac Acular Soln, 0.5% QID Nonsteroidal anti-inflammatory agentAcular PF Soln, 0.5% QID Presevative free in unit dose viallevocabastine Livostin Soln, 0.05% BID-QID H1-antagonist (preservative may damage contact lenses)lodeprednol etabonate Alrex Soln, 0.2% QD-QID Corticosteroid: must monitor for steroid complications,but is considered a “soft steroid” with less IOP andcataract effectsLotemax Soln, 0.5% QD-QID Same compound as Alrex at an increased concentration;Corticosteroid: must monitor for steroid complications,but is considered a “soft steroid” with less IOP andcataract effectslodoxamide Alomide Soln, 0.1% QID × 2–3 Mast cell inhibitor, possibly faster onset than cromolyn;weeks still takes a few weeks for full effectnedocromil Alocril Soln, 2% BID Mast cell stabilizerolopatadine Patanol Soln, 0.1% BID H1-antagonist with mast cell stabilizationpemirolast Alamast Soln, 0.1% QID Mast cell stabilizer