Douglas J. Rhee, MD

98E. ANESTHETIC AGENTS(1) Topical Anesthetics 1Drug Trade Preparation Dose Notesbenoxinate Fluress, Fluorox Soln, 0.4% with 0.25% 1 drop Duration 15–30 min, Ester linkage,fluorescein sodium preserved with chlorobutanolcocaine hydrochloride N/A Soln, 1%–4% 1 drop Duration 20–45 min, pupillarydilation, potentiates epinephrinebenoxinate Fluress, Fluorox Soln, 0.4% with 0.25% 1 drop Duration 15–30 min, Ester likage,fluorescein sodium preserved with chlorobutanolproparacaine AK-Taine , Alcaine , Ocu- Soln, 0.5% 1 drop Duration 15–30 min.Caine, Ophthaine , Ester linkage, Ophthetic preservedOphthetic with benzalkonium chlorideFluorocaine Soln, 0.5% with 0.25% 1 dropfluorescein sodiumtetracaine AK-T-Caine , Pontocaine Soln, 0.5% 1 drop Duration 9–24 min.Ester linkageNotes: 1. Topical anesthetics should only be used to allow the clinician to perform ocular procedures. They are not indicated for useby the patient and should never be prescribed.2. Allergies to topical anesthetic drops may be a reaction to the medication itself, class of linkage (e.g., amide versus ester), orsimply the preservative.