Douglas J. Rhee, MD

80D. MISCELLANEOUSDrug Trade Preparation Usual Dose Notescyclosporine Sandimmune Tablets, 25, 50, 100 mg 2.5–5.0 mg/kg/day Used for severe uveitis in children and adolescents 1Oral sol’n 100 mg/ml May have significant side effects, includingnephrotoxicity, hypertension, anemia, and gingivalhyperplasia. Serum drug levels, as well as serumcreatinine, hemoglobin, and blood pressure, mustbe monitoredSoln, 2% (in oil) QID For ligneous conjunctivitis and other inflammatoryconditionsQID × 3 months For steroid-dependent atopic keratoconjunctivitis 2Soln, 1% (in tears) QD–QID For prevention of graft rejectionFor inflammatory peripheral ulcerative keratitisRestasis Oil emulsion 0.05% BID FDA approved for the treatment of dry eyes1 From Ophthalmology 1998;105:2028–2034.2 From Ophthalmology 2004;111:476–482.