Douglas J. Rhee, MD

130APPENDIX 5. GLAUCOMA MEDICATION PRESERVATIVESThere is a growing body of literature indicating that higher concentrations of BAK are associated with inflammatory changes in theconjunctiva and even trabecular meshwork. 1 If a BAK allergy is suspected, one could consider a provocative test in one eye of a BAK preservedartifical tear to determine if the symptoms of redress and discomfort are re-created i.e. a BAK challenge test.Preservative Drug TradeNone timolol maleate Timoptic (ocu-dose)pilocarpine 2% & 4% generic (steri-unit)Benzalkonium chloride (BAK) 0.01% apraclonidine Iopidine0.01% betaxolol Betoptic0.005% bimatoprost Lumigan0.005% brimonidine Alphagan0.01% brinzolamide Azoptcarbachol Isopto Carbachol0.005% carteolol Carteolol HCldemecarium bromide Humorsoldipivefrin Propine0.0075% dorzolamide Trusoptepinephrine Epifrin0.02% latanoprost Xalatan0.004% levobunolol Betagan