Douglas J. Rhee, MD

10(d) CongenitalDrug Dosepenicillin G 50,000 U/kg IM or IV Q8–12 hr × 10–14 days(2) Gonococcal Conjunctivitis /Keratitis 3,4Notes: 1. Patient’s sexual partners must be treated. Both patient and sexual partners must be evaluated for other manifestations ofgonorrhea and for other sexually transmitted diseases, including HIV and syphilis.2. Patients must also be treated for concurrent chlamydial infection, which may be present.3. In penicillin/cephalosporin-allergic patients, consider ciprofloxacin 500 mg PO for one dose; an infectious disease consultmay be needed.4. All patients should receive warm saline irrigation of fornices.5. Also administer topical antibiotics:• Bacitracin or erythromycin ointment QID (may use ciprofloxacin, ofloxacin, gatifloxacin, or moxifloxacin soln Q2 hr [adultsonly]) for conjunctivitis only.• Gatifloxacin, moxifloxacin, ofloxacin, ciprofloxacin or gentamicin or tobramycin soln Q1 hr for corneal involvement.Drug Trade Dose Notesceftriaxone Rocephin 1 gram IM × 1 dose For adult GC conjunctivitis25–50 mg/kg IV QD × 7 days For child with GC conjunctivitis 5125 mg IM × 1 dose For neonatal gonococcal conjunctivitis ; do not use withhyperbilirubinemic neonates1 -2 gram IV QD × 3–5 days For adult GC corneal ulcercefotaxime Claforan 50 mg/kg IV or IM Q8–12 hr × 7 days For neonatal gonococcal conjunctivitis