Color Atlas of Hematology - Practical Microscopic and Clinical ...

Predominance of Mononuclear Round to Oval Cells93Table 14ContinuedM5 a) Acute monoblasticleukemia;monoblastspredominant inthe blood andbone marrowb) Acute monocyticleukemia;monocytes inthe process ofmaturation predominanteM6M7Acute erythroidleukemia; 50% ofbone marrow blastsare erythropoietic,30% myeloblastsAcute megakaryocyticleukemia; verypolymorphic, sometimesvacuolatedblasts, some withcytoplastic blebs,sometimes aggregatedwith thrombocytes +++ 80% +++ +++FAB type* Peroxidase PAS α-NaphthylacetateesteraseNaph-thyl-ASDesteraseImmunophenotype+++ CD 13/CD 33/CD 65/CD 14/CD64 /and HLA-DR ErythroblastsGly A andCD 36 MyeloblastsMPO/CD13/CD 33/CD65s / andCD 14 CD 13/CD 33/ und CD41 oder CD61 * French American British Classification (FAB) 1976/85** A biphenotypic leukemia must be considered a possibility if several additional lymphoblasticmarkers are presentPAS Periodic acid-Schiff reaction