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Color Atlas of Hematology - Practical Microscopic and Clinical ...

Color Atlas of Hematology - Practical Microscopic and Clinical ...

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Hypochromic anemia without iron deficiency, sometimes withtarget cells, suggests thalassemiaabcFig. 47 Thalassemia. a Thalassemia minor: <strong>of</strong>ten no target cells, but an increasein the number <strong>of</strong> small erythrocytes (shown here in comparison with a lymphocyte),so that sometimes there is no anemia. b More advanced thalassemia minor:strong anisocytosis <strong>and</strong> poikilocytosis (1), basophilic stippling (2), <strong>and</strong> sporadictarget cells (3). c Thalassemia major: erythroblasts (1), target cell (2), polychromaticerythrocytes (3), <strong>and</strong> Howell–Jolly bodies (4) (in a case <strong>of</strong> functional asplenia).Lymphocyte (5) <strong>and</strong> granulocyte (6).139

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