Color Atlas of Hematology - Practical Microscopic and Clinical ...

Lymph Node Cytology175Anamnesis– sudden fast swelling– possible onset in youth– possible contactwith animals– possible feverslow onset, unclearsymptoms: subfebrile,night sweat, weightlossFindings– pressure pain– focal, or distributedover severallocationsDindolent often in onelocation, possiblylocalization ofprimary tumorBloodanalysis– relative lymphocytosiswithstimulated formsspecific cell presentation(e.g. CLL, immunocytoma,ALL and others)Serology/ – mononucleosis testimmunology – toxoplasmosis– rubella– syphilis– tuberculin skin testDor unspecific signsor Searchfor diseasefocus– e.g. teeth– sinuses– infections ofthe genitalia– if findings arenegative or unsuccessfultherapyafter 1 weekconsidered reactive ifthe lymph node swellingdoes not recede after2 weeks or the causeis foundDLymph nodebiopsysuspicion of tumor ormalignant lymphomaattempt to clarifythe diagnosis after histologypossiblyDdiagnosis basedon histologyDiagnostic flow chart for cases of lymph node enlargement. (D) Diagno-Fig. 62sis.