Color Atlas of Hematology - Practical Microscopic and Clinical ...

130Erythrocyte and Thrombocyte AbnormalitiesTable 22 Diagnostic findings and work-up for the most important disorders ofthe red cell seriesClinicalfindingsHb MCH ErythrocytemorphologyReticulocytesLeukocytesSegmentednuclei(%)Lymphocytes(%)Other cellsThrombocytesFatigue,pallor(dysphagia) Ring-shapederythrocytes,anisocytosis n n n - n/Possibly Anisocytosis,fever, weightpoikilocytosisloss n/ n n Possiblyeosinophilsmonocytes left shiftnDiffusesymptoms /n/ All sizes,dimorphic n/ n n - n/Acute n n n n () () - n//hemorrhageSubjaundice n n or pathol., n/ n n Possibly normoblastspossiblyspherocytesn/Spleen Target cells n n n Possibly normoblastsnPallerpossiblyinfectionsand bleedingtendency n n PossiblymonocytesPallorpossiblyalcohol history Macrocytes,megalocytes Possiblyhypersegmentedgranulocytes,possibly normoblasts/nPlethora,possiblyspleen n n n n/ n n - n/Acute bleeding n n () n n n - tendencyDiagnostic steps proceed from left to right. ❘ The next step is usually unnecessary; : . the nextstep is optional; the next step is obligatory. n = normal value, = lower than normal, = elevated,( ) = test not relevant, BSG = erythrocyte sedimentation rate.