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322012-2014 General Catalog Course Supplement and Policies and Requirements Addendum130. Modeling of Dynamic Processes inBiological Systems (4)Lecture—3 hours; discussion—1 hour. Prerequisite:course 75; Engineering 6 or Computer Science &Engineering 30; grade of C- or better in Mathematics22B required for enrollment eligibility. Techniquesfor modeling processes through mass and energybalance, rate equations, and equations of state.Computer problem solution of models. Examplemodels include package design, evaporation, respirationheating, thermal processing of foods, andplant growth. GE credit: SciEng | OL, QL, SE, SL,VL.—II. (II.) K. McCarthy, Upadhyaya(change in existing course—eff. winter 13)135. Bioenvironmental Engineering (4)Lecture—3 hours; laboratory—3 hours. Prerequisite:courses 125, 130. Biological responses to environmentalconditions. Principles and engineering designof environmental control systems. Overview of environmentalpollution problems and legal restrictionsfor biological systems, introduction of environmentalquality assessment techniques, and environmentalpollution control technologies. GE credit:SciEng | QL, SE, SL, VL, WE.—I. (I.) Jenkins, Zhang(change in existing course—eff. winter 13)144. Groundwater Hydrology (4)Lecture—4 hours. Prerequisite: Mathematics 16B or21A; Hydrologic Science 103 or Engineering 103recommended. Fundamentals of groundwater flowand contaminant hydrology. Occurrence, distribution,and movement of groundwater. Well-flow systems.Aquifer tests. Well construction operation andmaintenance. Groundwater exploration and qualityassessment. Agricultural threats to groundwater quality:fertilizers, pesticides, and salts. Same course asHydrologic Science 144. GE credit: SciEng | QL,SE, SL, VL.—I. (I.) Fogg(change in existing course—eff. winter 13)145. Irrigation and Drainage Systems (4)Lecture—4 hours. Prerequisite: course 103 or HydrologicScience 103N. Engineering and scientific principlesapplied to the design of surface, sprinkle andmicro irrigation systems and drainage systems withineconomic, biological, and environmental constraints.Interaction between irrigation and drainage.GE credit: SciEng | QL, SE, SL, VL.—II. (II.) Grismer,Wallender(change in existing course—eff. fall 13)147. Runoff, Erosion and Water QualityManagement in the Tahoe Basin (3)Lecture/laboratory—30 hours; fieldwork—15 hours;discussion—10 hours; term paper. Prerequisite:Physics 7B or 9B, Mathematics 16C or 21C, Civiland Environmental Engineering 142 or HydrologicScience 141 or Environmental and Resource Sciences100. Five days of instruction in Tahoe City.Practical hydrology and runoff water quality managementfrom Tahoe Basin slopes. Development ofhillslope and riparian restoration concepts, modelingand applications from physical science perspectivesincluding precipitation-runoff relationships, sedimenttransport, and detention ponds. (Same course asHydrologic Science 147.) GE credit: SciEng | QL,SE, SL.—Grismer(change in existing course—eff. winter 13)161. Kinetics and Bioreactor Design (4)Lecture—3 hours; discussion—1 hour. Prerequisite:course 127. Provide the basic principles of reactordesign for bioprocess applications. This courseemphasizes the following topics: 1) kinetics andreactor engineering principles; 2) bio-reaction kinetics;and 3) bioreactor design. GE credit:SciEng | QL, SE, VL.—II. (II.) Fan, Zicari(change in existing course—eff. winter 13)165. Bioinstrumentation and Control (4)Lecture—3 hours; laboratory—3 hours. Prerequisite:Engineering 100. Instrumentation and control forbiological production systems. Measurement systemconcepts, instrumentation and transducers for sensingphysical and biological parameters, data acquisitionand control. GE credit: SciEng | QL, SE, SL,VL, WE.—I. (I.) Delwiche, Slaughter(change in existing course—eff. winter 13)170A. Engineering Design and ProfessionalResponsibilities (3)Lecture—2 hours; laboratory—3 hours. Prerequisite:course 1, Engineering 102, 104. Engineeringdesign including professional responsibilities.Emphasis on project selection, data sources, specifications,human factors, biological materials, safetysystems, and professionalism. Detailed design proposalswill be developed for courses 170B and170BL. GE credit: SciEng | OL, QL, SE, SL, VL,WE.—I. (I.) Giles, Zhang(change in existing course—eff. winter 13)170B. Engineering Projects: Design (2)Discussion—2 hours. Prerequisite: course 170A;course 170BL required concurrently. Individual orgroup projects involving the design of devices, structures,or systems to solve specific engineering problemsin biological systems. Project for study is jointlyselected by student and instructor. GE credit:SciEng | OL, QL, SE, SL, VL, WE.—II. (II.) Giles,Zhang(change in existing course—eff. winter 13)170BL. Engineering Projects: DesignLaboratory (1)Laboratory—3 hours. Prerequisite: course 170Brequired concurrently. Individual or group projectsinvolving the design of devices, structures, or systemsto solve specific engineering problems in biologicalsystems. GE credit: SciEng | OL, QL, SE, SL, VL,WE.—II. (II.)(change in existing course—eff. winter 13)170C. Engineering Projects: DesignEvaluation (1)Discussion—1 hour. Prerequisite: course 170B;required to enroll in course 170CL concurrently. Individualor group projects involving the fabrication,assembly and testing of components, devices, structures,or systems designed to solve specific engineeringproblems in biological systems. Project for studypreviously selected by student and instructor incourse 170B. GE credit: SciEng | OL, QL, SE, SL,VL, WE.—III. (III.) Giles, Zhang(change in existing course—eff. winter 13)170CL. Engineering Projects: DesignEvaluation (2)Laboratory—6 hours. Prerequisite: required to enrollin course 170C concurrently. Individual or groupprojects involving the fabrication, assembly and testingof components, devices, structures, or systemsdesigned to solve specific engineering problems inbiological systems. GE credit: SciEng | OL, QL, SE,SL, VL, WE.—III. (III.)(change in existing course—eff. winter 13)175. Rheology of Biological Materials (3)Lecture—3 hours. Prerequisite: course 103 or Engineering103. Fluid and solid rheology, viscoelasticbehavior of foods and other biological materials,and application of rheological properties to foodand biological systems (i.e., pipeline design, extrusion,mixing, coating). GE credit: SciEng | QL, SE,VL.—II. (II.) McCarthy(change in existing course—eff. fall 13)189A-G. Special Topics in BiologicalSystems Engineering (1-5)Variable—3-15 hours. Prerequisite: upper divisionstanding in engineering; consent of instructor. Specialtopics in: (A) Agricultural Engineering; (B) AquaculturalEngineering; (C) Biomedical Engineering;(D) Biotechnical Engineering; (E) Ecological SystemsEngineering; (F) Food Engineering; and (G) ForestEngineering. May be repeated for credit when topicdiffers. GE credit: SciEng | SE.—I, II, III. (I, II, III.)(change in existing course—eff. winter 13)190C. Research Group Conference inBiological Systems Engineering (1)Discussion—1 hour. Prerequisite: upper divisionstanding in Biological Systems Engineering or FoodEngineering; consent of instructor. Research groupconference. May be repeated for credit. (P/NPgrading only.) GE credit: SE.—I, II, III. (I, II, III.)(change in existing course—eff. winter 13)192. Internship in Biological SystemsEngineering (1-5)Internship. Prerequisite: upper division standing;approval of project prior to period of internship.Supervised work experience in biological systemsengineering. May be repeated for credit. (P/NPgrading only.) GE credit: SE.(change in existing course—eff. winter 13)197T. Tutoring in Biological SystemsEngineering (1-5)Tutorial—3-15 hours. Prerequisite: upper divisionstanding. Tutoring individual students, leading smallvoluntary discussion groups, or assisting the instructorin laboratories affiliated with one of the department’sregular courses. May be repeated for credit iftopic differs. (P/NP grading only.) GE credit: SE.(change in existing course—eff. winter 13)198. Directed Group Study (1-5)Prerequisite: consent of instructor. (P/NP gradingonly.) GE credit: SE.(change in existing course—eff. winter 13)199. Special Study for AdvancedUndergraduates (1-5)(P/NP grading only.) GE credit: SE.(change in existing course—eff. winter 13)Engineering:BiomedicalNew and changed courses inBiomedical Engineering (BIM)Lower Division20. Fundamentals of Bioengineering (4)Lecture—3 hours; discussion—1 hour. Prerequisite:C- or better in Chemistry 2B and Mathematics 21D;Physics 9B. Basic principles of mass, energy andmomentum conservation equations applied to solveproblems in the biological and medical sciences.Only two units of credit to students who have previouslytaken Chemical Engineering 51, Engineering105. GE credit: SciEng | QL, SE, VL.—III. (III.) Silva(change in existing course—eff. fall 13)89A. Topics in Biomedical Engineering (1-5)Prerequisite: consent of instructor. Restricted to lowerdivision students. Topics in Biomedical Engineering.(A) Cellular and Molecular Engineering. May berepeated for credit when topic differs. GE credit:SciEng | SE.(change in existing course—eff. winter 13)89B. Topics in Biomedical Engineering (1-5)Prerequisite: consent of instructor. Restricted to lowerdivision students. Topics in Biomedical Engineering.(B) Biomedical Imaging. May be repeated for creditwhen topic differs. GE credit: SciEng | SE.(change in existing course—eff. winter 13)Quarter Offered: I=Fall, II=Winter, III=Spring, IV=Summer; 2013-2014 offering in parenthesesPre-Fall 2011 General Education (GE): ArtHum=Arts and Humanities; SciEng=Science and Engineering; SocSci=Social Sciences; Div=Domestic Diversity; Wrt=Writing ExperienceFall 2011 and on General Education (GE): AH=Arts and Humanities; SE=Science and Engineering; SS=Social Sciences;ACGH=American Cultures; DD=Domestic Diversity; OL=Oral Skills; QL=Quantitative; SL=Scientific; VL=Visual; WC=World Cultures; WE=Writing Experience
2012-2014 General Catalog Course Supplement and Policies and Requirements Addendum3389C. Topics in Biomedical Engineering (1-5)Prerequisite: consent of instructor. Restricted to lowerdivision students. Topics in Biomedical Engineering.(C) Biomedical Engineering. May be repeated forcredit when topic differs. GE credit: SciEng | SE.(change in existing course—eff. winter 13)99. Special Study for Undergraduates (1-5)(P/NP grading only.) GE credit: SE.(change in existing course—eff. winter 13)Upper Division102. Quantitative Cell Biology (4)Lecture/discussion—4 hours. Prerequisite: BiologicalSciences 2A; Chemistry 8B. Fundamental cell biologyfor bioengineers. Emphasis on physical conceptsunderlying cellular processes including proteintrafficking, cell motility, cell division and cell adhesion.Current topics including cell biology of cancerand stem cells will be discussed. Only two units ofcredit for students who have completed BiologicalSciences 104 or Molecular and Cellular Biology143. GE credit: SciEng | QL, SE, VL.—I. (I.)Yamada(change in existing course—eff. fall 13)105. Probability and Statistics forBiomedical Engineers (4)Lecture—3 hours; discussion—1 hour. Prerequisite:C- or better in Mathematics 21D; Engineering 6(may be concurrent). Concepts of probability, randomvariables and processes, and statistical analysiswith applications to engineering problems in biomedicalsciences. Includes discrete and continuousrandom variables, probability distributions and models,hypothesis testing, statistical inference and Matlabapplications. Emphasis on BME applications. GEcredit: SciEng | QL, SE, VL.—I. (I.) Saiz(change in existing course—eff. fall 13)106. Biotransport Phenomena (4)Lecture—4 hours. Prerequisite: C- or better in course20; course 116 or Neurobiology, Physiology, andBehavior 101; Physics 9B; Mathematics 22B. Opento Biomedical Engineering majors only. Principles ofmomentum and mass transfer with applications tobiomedical systems; emphasis on basic fluid transportrelated to blood flow, mass transfer across cellmembranes, and the design and analysis of artificialhuman organs. GE credit: SciEng | QL, SE, SL,VL.—II. (II.) Leach(change in existing course—eff. fall 13)107. Mathematical Methods for BiologicalSystems (4)Lecture—3 hours; discussion—1 hour. Prerequisite:C- or better in Engineering 6; course 20; Mathematics22B. Restricted to Biomedical Engineering majorsonly. Mathematical and computational modeling tosolve biomedical problems. Topics include stochasticprocesses and Monte Carlo simulations, and partialdifferential equations. Introduced to numerical techniquesin MATLAB. GE credit: SciEng | QL, SE,VL.—II. (II.) Duan(change in existing course—eff. fall 13)109. Biomaterials (4)Lecture—4 hours. Prerequisite: course 106; BiologicalSciences 2A; Chemistry 2C. Restricted to upperdivisionEngineering majors. Introduce importantconcepts for design, selection and application ofbiomaterials. Given the interdisciplinary nature ofthe subject, principles of polymer science, surfacescience, materials science and biology will be integratedinto the course. GE credit: SciEng | SE, SL,VL.—III. (III.) Revzin(change in existing course—eff. fall 13)110A. Biomedical Engineering SeniorDesign Experience (3)Lecture/discussion—1 hour; project—6 hours. Prerequisite:course 110L. Restricted to senior BiomedicalEngineering majors (or by consent of instructor).Application of bioengineering theory and experimentalanalysis to a design project culminating inthe design of a unique solution to a problem. Designmay be geared towards current applications in biotechnologyor medical technology. Continues incourse 110B. (Deferred grading only, pending completionof sequence.) GE credit: SciEng | OL, SE, SL,VL.—II. (II.) Louie, Passerini(change in existing course—eff. winter 14)110B. Biomedical Engineering SeniorDesign Experience (3)Lecture/discussion—1 hour; project—6 hours. Prerequisite:course 110A. Application of bioengineeringtheory and experimental analysis to a designproject culminating in the design of a unique solutionto a problem. Design may be geared towards currentapplications in biotechnology or medical technology.(Deferred grading only, pending completionof sequence.) GE credit: SciEng | OL, SE, SL, VL.—III. (III.) Louie, Passerini(change in existing course—eff. spring 14)110L. Biomedical Engineering SeniorDesign Lab (2)Laboratory—3 hours; laboratory/discussion—2hours. Prerequisite: courses 105, 108, 109.Restricted to Senior Biomedical Engineering majors.Manufacturing processes, safety, and computeraideddesign techniques applied to the fabricationof biomedical devices. Application of bioengineeringprinciples and design theory to a project culminatingin completion of a functional prototype thatsolves a biomedical problem. Continues in 110AB.(Deferred grading only, pending completion ofsequence.) GE credit: SciEng | SE.—I. (I.) Louie,Passerini(change in existing course—eff. fall 13)111. Biomedical InstrumentationLaboratory (6)Lecture—4 hours; discussion/laboratory—4 hours.Prerequisite: courses 105, 107 and 108; Engineering100 or Electrical Engineering 100; course 116or Neurobiology, Physiology, & Behavior 101.Open to Biomedical Engineering majors only. Basicbiomedical signals and sensors. Topics include analogand digital records using electronic, hydrodynamic,and optical sensors, and measurementsmade at cellular, tissue and whole organism level.GE credit: SciEng | QL, SE, SL.—II. (II.) Marcu, Pan(change in existing course—eff. fall 13)116. Physiology for Biomedical Engineers(5)Lecture—2 hours; discussion—3 hours. Prerequisite:C- or better in Biological Sciences 2A; Physics 9C;Mathematics 22B recommended. Basic human physiologyfor the nervous, musculoskeletal, cardiovascular,respiratory, gastrointestinal, renal, andendocrine systems. Emphasis on small group designprojects and presentations in interdisciplinary topicsrelating biomedical engineering to medical diagnosticand therapeutic applications. GE credit:SciEng | OL, SE, SL, VL, WE.—I. (I.) Louie(change in existing course—eff. fall 13)117. Analysis of Molecular and CellularNetworks (4)Lecture—3 hours; discussion—1 hour. Prerequisite:grade of C- or better in Biological Sciences 2A andMathematics 22A. Restricted to upper division standing.Network themes in biology, emphasizing metabolic,genetic, and developmental networks.Mathematical and computational methods for analysisof such networks. Elucidation of design principlesin natural networks. Engineering and ethical issuesin the design of synthetic networks. Offered alternateyears. GE credit: SciEng | QL, SE, SL, VL.—III. Savageau(change in existing course—eff. fall 12)118. Microelectromechanical Systems (4)Lecture—2 hours; laboratory—3 hours; discussion—1 hour. Prerequisite: Chemistry 2A; Engineering 100or Electrical and Computer Engineering 100.Restricted to upper division standing in College ofEngineering. Introduction to the theory and practiceof micro-electromechanical systems (MEMS), includingfundamentals of micro-nanofabrication,microscale sensing and actuation, self assembly,microfluidics and lab-on-a-chip. Weekly hands-onlaboratory sections are emphasized on implementationand utilization of MEMS technologies. (Samecourse as Electrical and Computer Engineering147.) GE credit: SciEng | QL, SE.—II. (II.) Pan(change in existing course—eff. winter 13)126. Tissue Mechanics (3)Lecture—2 hours; laboratory/discussion—3 hours.Prerequisite: Exercise Science 103 and/or Engineering45 and/or consent of instructor. Structural andmechanical properties of biological tissues, includingbone, cartilage, ligaments, tendons, nerves, andskeletal muscle. (Same course as Exercise Biology126.) GE credit: SciEng | QL, SE, SL, WE.—II. (II.)Hawkins(change in existing course—eff. winter 13)140. Protein Engineering (4)Lecture—3 hours; discussion—1 hour. Prerequisite:Biological Sciences 2A. Introduction to protein structureand function. Modern methods for designing,producing, and characterizing novel proteins andpeptides. Design strategies, computer modeling, heterologousexpression, in vitro mutagenesis. Proteincrystallography, spectroscopic and calorimetricmethods for characterization, and other techniques.Offered in alternate years. GE credit: SciEng | QL,SE, SL, VL.—III. Facciotti(change in existing course—eff. fall 13)141. Cell and Tissue Mechanics (4)Lecture—3 hours; discussion—1 hour. Prerequisite:Physics 9B; Engineering 6; Engineering 35.Mechanical properties that govern blood flow in themicrocirculation. Concepts in blood rheology andcell and tissue viscoelasticity, biophysical aspects ofcell migration, adhesion, and motility. GE credit:SciEng | QL, SE, VL.—II. (II.) Parikh(change in existing course—eff. fall 13)142. Principles and Practices of BiomedicalImaging (4)Lecture—4 hour. Prerequisite: Physics 9D, Mathematics22B, course 108 (may be taken concurrently).Basic physics, engineering principles, and applicationsof biomedical imaging techniques including x-ray imaging, computed tomography, magnetic resonanceimaging, ultrasound and nuclear imaging. GEcredit: SciEng | QL, SE, SL, VL.—III. (III.) Ferrara(change in existing course—eff. winter 13)143. Biomolecular Systems Engineering:Synthetic Biology (4)Lecture—3 hours; discussion—1 hour. Prerequisite:Biological Sciences 2A; Mathematics 16C or equivalent.Includes analysis, design, construction andcharacterization of molecular systems. Process andbiological parts standardization, computer aideddesign, gene synthesis, directed evolution, proteinengineering, issues of human practice, biologicalsafety, security, innovation, and ethics are covered.Offered in alternate years. GE credit:SciEng | SE.—III. Facciotti(change in existing course—eff. fall 13)151. Mechanics of DNA (3)Lecture—3 hours. Prerequisite: Biological Sciences2A and Mathematics 22B. Structural, mechanicaland dynamic properties of DNA. Topics includeDNA structures and their mechanical properties, invivo topological constraints on DNA, mechanicaland thermodynamic equilibria, DNA dynamics, andQuarter Offered: I=Fall, II=Winter, III=Spring, IV=Summer; 2013-2014 offering in parenthesesPre-Fall 2011 General Education (GE): ArtHum=Arts and Humanities; SciEng=Science and Engineering; SocSci=Social Sciences; Div=Domestic Diversity; Wrt=Writing ExperienceFall 2011 and on General Education (GE): AH=Arts and Humanities; SE=Science and Engineering; SS=Social Sciences;ACGH=American Cultures; DD=Domestic Diversity; OL=Oral Skills; QL=Quantitative; SL=Scientific; VL=Visual; WC=World Cultures; WE=Writing Experience
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