Boreskov

PP‐16FROM PRIMARY DNAs TO CELLS: LIFE ORIGINATION HYDRATE HYPOTHESIS(LOH‐HYPOTHESIS)Kadyshevich E.A. 1 2and Ostrovskii V.E.1 Obukhov Institute of Atmospheric Physics RAS, Moscow, Russia, kadyshevich@mail.ru2 Karpov Institute of Physical Chemistry, Moscow, Russia, vostrov@cc.nifhi.ac.ru1. IntroductionWe believe that the DNA origination and replication is governed by a physicochemicalprocess of the same nature, namely, by the formation–destruction of the honeycombhydrate structures around each N‐basis. Cells are no more than the chambers that protectDNAs from the rivalry for the nutrients and space. The main differences between DNAsorigination and replication consist in the occurrence, during replication, of inoculating DNAsin each cell, in the specificity of the nutrient soup composition, and in somewhat enhancedtemperature, which is, however, so low that it doesn’t allow disruption of thethermodynamically‐caused sequence of chemical reactions; and the main similaritiesbetween these processes consist in the disutility of any agitation, in the occurrence ofcarbon, quinquivalent nitrogen, and quinquivalent phosphorous mixture in the soupcomposition, and in a rather low temperature.2. From primary DNSs to replicating cellsAccording to the LOH‐hypothesis [1–8], the N‐bases, riboses, nucleozides, nucleotides(living matter simplest elements (LMSEs)) and also DNA‐ and RNA‐like molecules formedwithin the CH 4 ‐hydrate structural cavities. Then, as H 2 O, NO – 3 , and PO 3– 4 diffused into thesystem, the structure liquidized and transformed into a structured soup (super‐cytoplasm)[2, 8], in which the simplest living organisms began the long history of their developmentand expansion over the world. In the super‐cytoplasm, all the substances, necessary for theexistence and development of the primary DNA‐ and RNA‐like molecules, and amino‐acids,could be synthesized on the basis of CH 4 and of NO – 3 , and PO 3– 4 that diffused from theenvironment [1, 2, 8]. Nucleic acids were shown to self‐replicate [9–12]; we proposed apossible mechanism of this process. Under appropriate conditions, these processes led to anincrease in the concentrations of nucleic acids and organophosphorous substances withinthe super‐cytoplasm. Increasing in their concentrations to a certain critical level led toprecipitation of phosphor‐containing membranes around DNAs with origination of proto‐158