PHARM 310 PHARMACEUTICS-I (Physical <strong>Pharmacy</strong>-I) [Th.]Cr. Hr.: 03 Marks: 1001. PHARMACY ORIENTATION:Introduction and orientation to the Professional of <strong>Pharmacy</strong> in relation to Hospital<strong>Pharmacy</strong>, Retail <strong>Pharmacy</strong>, Industrial <strong>Pharmacy</strong>, Forensic <strong>Pharmacy</strong>,Pharmaceutical education and research etc.2. HISTORY AND LITERATURE OF PHARMACY:a. A survey of the history of pharmacy through ancient, Greek and Arabperiods with special reference to contribution of Muslim scientists topharmacy and allied sciences.b. An introduction of various official books.3. PHYSICO-CHEMICAL PRINCIPLES:a. Solutions: Introduction, types, concentration expressions, ideal and realsolution, colligative properties, their mathematical derivations andapplications in pharmacy, molecular weight determinations, distributionco-efficient and its applications in pharmacy.b. Solubilization: Solubility, factors affecting solubility, surfactants, theirproperties and types. Micelles, their formulation and types.c. Ionization, pH, pH indicators, pka, buffers, buffer’s equation, Isotonicsolutions and their applications in pharmacy.d. Hydrolysis, types and protection of drugs against hydrolysis.e. Micromeritics: Particle size and shapes, distribution of particles methodsof determination of particle size and importance of particle size in<strong>Pharmacy</strong>.4. DISPERSIONS:a. Colloids: Types, methods of preparation, properties (optional, kinetic,electrical) Dialysis and artificial kidney, stability of colloids, protection andsensitization phenomenon and application of colloids in <strong>Pharmacy</strong>.b. Emulsions: Types, theories of emulsification, Emulsifying agents theirclassification and stability of emulsion.c. Suspensions: Type, Methods of Preparation, Properties, Suspending agents,their classification and stability.d. Adsorption: Techniques and processes of adsorption in detail.12 | Pakistan Pharmacist Federation; www.pharmacistfed.pk,www.pharmafed.wordpress.com, www.pharmarev.com, info@pharmacistfed.pk,
PHARM 311 PHARMACEUTICS-I (Physical <strong>Pharmacy</strong>-I) [Lab.]Cr. Hr.: 01 Marks: 50NOTE:- Practicals of the subject shall be designed from time to time on the basisof the above mentioned theoretical topics and availability of the facilities,e.g.1. Determination of Emulsion systems.2. Determination of particle size.3. Density, Specific Volume, Weights and Volumes of Liquids.4. Preparation of Buffer solutions and isotonic solution.5. Determination of %age composition of solutions by specific gravity method.Recommended Books:1. Martin, Physical <strong>Pharmacy</strong>, B I Waverly PVT, Delhi, 5th Ed., 2005.2. Cooper and Gunns Tutorial <strong>Pharmacy</strong>, 6 th Ed, CBS Publishers &Distributors, New Delhi, 2005.3. Bentley’s Pharmaceutics, All India Traveler Book Seller, New Delhi, 1996.4. Martin P, Bustamante P and Chun, Physical & Chemical Principles ofPharmaceutical Science, AHC, 6th Ed., (1999), New York.5. Martin AMN, Banker G S and Chun AHC Advances in PharmaceuticalSciences. Vol 7,Academic Press, London, 1995.6. Mill C C Casson,N.Rheology of disperse systems. Pergamon Press, NewYork, 1975.7. Rienger M and Scott-Blair. G W Rheology.Academic Press, London, 1990.8. Barry B W Advances in Pharmaceutical Sciences, Academic Press,London, 1990.9. Sherman P Emulsion Science, Academic Press, London, 1972. 1 0.Martin A,Swarbrick J and Cammatra A10. Physical <strong>Pharmacy</strong>, 3rd Ed., Lee& Febiger, Philadelphia. 1983.11. Attwood D and Flocence A T Surfactant Systems.Chapman and Hall Ltd,London,1982.PHARM 312 PHARMACEUTICAL CHEMISTRY-I (ORGANIC-I)[Th.]Cr. Hr.: 03 Marks: 100Note: The topics will be taught with special reference to their PharmaceuticalApplications.1. BASIC CONCEPTS: Chemical Bonding and concept of Hybridization,Conjugation, Resonance (Mesomerism), Hyperconjugation, Aromaticity,Inductive Effect, Electromeric, Effect, Hydrogen bonding, Steric Effect, Effect13 | Pakistan Pharmacist Federation; www.pharmacistfed.pk,www.pharmafed.wordpress.com, www.pharmarev.com, info@pharmacistfed.pk,
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RecommendationsAll members of NCRC