acid, Proteins, Lipids and Sterols (Cholesterol) Bile salts and billirubin, Billirubin,Blood analysis-Cholesterol and Creatinine.Recommended Books:1. M N Chaterjea, Medical Biochemistry, 7 th Ed, Jaypee Brothers MedicalPublishers, New Delhi, 2007.2. Roberk Murray, Daryl K, Granner, Peter A Mayes, Victor W Rodwell Harper’sBiochemistry, 28 th Ed,Appleton and Lange, Lange Medical Publications, NewYork, 2009.3. Albert L Lehninger Principles of Biochemistry, 4 th Ed, CBS Publisher,Delhi,2004.4. Lubert Stryer, Biochemistry, 5 th Ed, W H Freeman and Company, 2002.5. Pamela C Champe, Richard A Harvey, Illustrated Biochemistry, 4 th Ed, JLippincot Company, 2007.6. Harper’s Biochemistry, 26 th Ed, Print-Hall, New Jersey, 2003.7. M Rafiq, Biochemistry, The Carvan Book House, Lahore, 1stEd.8. Montogomary, Clinical Chemistry, the C V Mosby Company, 5th Ed.9. Conn and Stumpf, Outlines of Biochemistry, John Willey & Sons, New York,5th Ed., 1999.10. Lehninger, Principles ofBiochemistry, 4th EdWorth Publishers Co, New York.200411. Ahmed M Essentials of Medical Biochemistry, Merit Pub Fasilabad, 1991.12.West E S, Todd R W and Van Bruggen T J, Text Book of Biochemistry, TheMacMillan Co, 1996.PHARM 316 PHYSIOLOGY-I [Th.]Cr. Hr.: 03 Marks: 100Course objectiveAfter the completion of this course the students should be able to describe all thebasic physiological processes which are the basis of pathophysiology of variousdiseases and their ultimate link with pharmacology for their treatment.1. Basic Cell Functionsa. Chemical composition of the body: Atoms, Molecules, Ions, FreeRadicals, Polar Molecules, Solutions, Classes of Organic Moleculesb. Cell structure: Microscopic Observation of Cell, Microscopic, CellOrganelles, Cytoskeleton.c. Protein activity and cellular metabolism: Binding Site Characteristics,Regulation of Binding site Characteristics, Chemical Reactions,Enzymes, Regulation of Enzyme – Mediated Reactions, Multienzymemetabolic Pathways, ATP, Cellular Energy Transfer, Carbohydrate, Fat,and Protein Metabolism, Essential Nutrients.d. Genetic information and Protein Synthesis: Genetic Code, ProteinSynthesis, Protein, Degradation, Protein Secretion, Replication and16 | Pakistan Pharmacist Federation; www.pharmacistfed.pk,www.pharmafed.wordpress.com, www.pharmarev.com, info@pharmacistfed.pk,
Expression of Genetic Information, Cancer, Genetic Engineering.e. Movement of Molecules across Cell Membranes: Diffusion, Mediated –Transport Systems, Osmosis, Endocytosis and Exocytosis, EpithelialTransport.2. Biological Control Systema. Homeostatic Mechanisms and Cellular Communication: GeneralCharacteristics, Components of Homeostatic Control Systems,Intercellular Chemical Massagers, Processes Related to Homeostasis,Receptors, single Transduction Pathways.b. Neural Control Mechanisms: Structure and Maintenance of Neurons,Functional Classes of Neurons, Glial Cells, Neural Growth andRegeneration, Basic Principles of Electricity, The resting MembranePotential, Graded Potentials and Action Potentials, FunctionalAnatomy of synapses, Activation of the Postsynaptic Cell, SynapticEffectiveness, Neurotransmitters and Neuromodulators, Neuroeffectorcommunication, Central Nervous System: spinal Cord Central NervousSystem: Brain, Peripheral Nervous System, Blood Supply, Blood-Brain Barrier Phenomena, and Cerebrospinal fluid.c. The Sensory Systems: Receptors, Neural Pathways in Sensory System,Association Cortex and Perceptual Processing, Primary SensoryCoding, somatic Sensation, Visio, Hearing, Vestibular System,Chemical Senses.d. Principles of Hormonal Control Systems: Hormone Structures andSynthesis, Hormone Transport in the Blood, Hormone Metabolism andExcretion, Mechanisms of Hormone Action, Inputs that controlHormone Secretion, control Systems Involving the Hypothalamus andPituitary, candidate Hormones, type of Endocrine Disorders.e. Muscle: Structure, Molecular Mechanisms of Contraction, Mechanicsof Single fiber Contraction, Skeletal Muscle Energy Metabolism,Types of Skeletal Muscle Fibers, Whole Muscle Contraction,Structure, Contraction and its Control.f. Control of Body Movement: Motor Control Hierarchy, Local controlof Motor Neurons, The Brain Motor Centers and the DescendingPathways they Control, Muscle Tone, Maintenance of Upright Postureand Balance, Walking.g. Consciousness and Behavior: State of consciousness, consciousExperiences, Motivation and Emotion, Altered State of Consciousness,Learning and Memory, Cerebral Dominance and language Conclusion.Note: Special emphases should be given on the normal physiologicalvalues and their changes during respective paqthological conditions.Further more, the physiological link will be developed with pathologyas well as pharmacology.PHARM 317PHYSIOLOGY-I [Lab.]Cr. Hr.: 01 Marks: 5017 | Pakistan Pharmacist Federation; www.pharmacistfed.pk,www.pharmafed.wordpress.com, www.pharmarev.com, info@pharmacistfed.pk,
- Page 1 and 2: NATIONAL CURRICULUM REVISIONCOMMITT
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vaccines.5. MISCELLANEOUS DETERMINA
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PHARM 722 PHARMACY PRACTICE-XIII (C
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3. The Pharmacy Act 1967.4. The Poi
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6. Block, Roche, Soine and Wilson.
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Experiences, Motivation and Emotion
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effervescent, granulated salts. Har
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Parasympathetic antagonists.f. Gang
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Sources, structure, preparation, de
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Microbiology with special reference
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Objectives• Develop vision of his
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their identification. Isolation and
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Delhi, 1986.4. Remington’s Pharma
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F I N A L P R O F E S S I O N A LPH
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Horwood Publishing limited, West Su
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RecommendationsAll members of NCRC