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GENERAL PROPERTIES, CHEMISTRY BIOLOGICALACTION,STRUCTURE ACTIVITY RELATIONSHIP ANDTHERAPEUTICAPPLICATIONS OF THE FOLLOWING:i. Sulphonamides: Prontosil, sulphanilamide, Sulphapyridine,sulphadimidine, Sulfamethoxazole, Sulfadiazine and Sulfafurazole.ii. Antimalarials: 4-Aminoquinolines, 8-Aminoquinolines, 9-Amino acridines,Biguanides, Pyrimidine analogues, Mefloquine and Cinchoha alkaloids.iii. Diuretics: Mercaptomerin, Meralluride, Thiazides, Sprironolac-tone,Theophylline, Furosemide, Acetazolamide, Ethacrynic acid and Triameterene.iv. Antitubercular Drugs: Ethambutol, Isonicotinic acid, Hydrazid, Rifampacin,Thioguanine, Pyrazinamide, cycloserine, Ethunamide, Cytarabine, 5-Flourouracil and Dacarbazine.v. Antiviral Drugs: Acyclovir, Tromantadine Hydrochloride and Ribavirin.vi. Immunosuppressant Agents: Azathioprine and Cyclosporin.vii. Antibiotics:Penicillins, Cephalosporins, Streptomycin, Chloramphenicol,Tetracyclines, Kanamycin and Erythromycin.PHARM 729 PHARMACEUTICAL CHEMISTRY-VI (Medicinal Chemistry-II)[Lab.]Cr. Hr.: 01 Marks: 50NOTE:- Practical of the subject shall be designed from time to time on the basis of theabove mentioned theoretical topics and availability of the facilities, e.g.Estimation of functional groups; Carboxylic, Hydroxy, Amino and Nitrogroups; Determination of Molecular weights of Organic Compounds. Synthesisof Paracetamol, Salicylic Acid, Methyl salicylate, Azobenzene, Benzoic Acid, 5-Hydroxy-1, 3-benzoxazol-2-one, Aspirin, P-nitrosophenol, 3-nitrophthalic acid,o-Chloro-benzoic acid. Assay of the Drugs like Sulpha drugs, Aspirin,Paracetamol, Benzyl Penicillin. Inorganic Preparations.(Note: A minimum of 10 practicals will be conducted)Recommended Books:1. Martin and Cook, Remington Practice of Pharmaceutical Science, 12 thEd,Mack Publishing Company, USA, 20012. Foye W O, Principles of Medicinal Chemistry, 6 th Ed, Verghese PublisingHouse, Bomby, 2008.3. Tyagi, Textbook of Synthetic Drugs, Anmol Publications, Delhi, 1990.4. Alferd Burger, Medicinal Chemistry, 6 th Ed, Jhon Willey & Sons, New York,2003.5. Block, Roche, Soine and Wilson, Inorganic and Medicinal PharmaceuticalChemistry, Verghese Publishing House, Bombay, 1986.90 | Pakistan Pharmacist Federation; www.pharmacistfed.pk,www.pharmafed.wordpress.com, www.pharmarev.com, info@pharmacistfed.pk,
6. Block, Roche, Soine and Wilson. Inorganic and Medicinal PharmaceuticalChemistry, Lee & Febiger, Philadelphia, USA, 1983.-----------------------------------------------------------------------------------------------------------NOTE: Upon completion of recognized Pharm. D. degree, a pharmacy graduateis required to undergo residency based training for a period of 1 year inany area; at general or private Hospital, pharmaceutical industry,community pharmacy, marketing, research & development and publichealth recognized by the Pharmacy Council of Pakistan. The objective ofthe residency is to undergo a planned training on aspects of pharmacypractice under the supervision of a registered pharmacist. After passingthe Pharmacy examination and completing 1 year of residency, graduatesare eligible to register with the Pharmacy Council and may practice as aregistered pharmacist in Pakistan.FACULTY OF PHARMACYThe faculty will comprise of the following departments with relevant subjects1. Department of Pharmaceutics• Pharmaceutics-I (Physical Pharmacy)• Pharmaceutics-II (Dosage Forms Science)• Pharmaceutics-III (Pharmaceutical Microbiology & immunology)• Pharmaceutics-IV(Industrial Pharmacy)• Pharmaceutics-V (Biopharmaceutics)• Pharmaceutics-VI (Pharmaceutical Quality Management)• Pharmaceutics-VII (Pharmaceutical Technology)2. Department of Pharmaceutical Chemistry• Pharmaceutical Chemistry-I (Organic Chemistry)• Pharmaceutical Chemistry-II (Biochemistry)• Pharmaceutical Chemistry-III (Pharmaceutical Analysis)• Pharmaceutical Chemistry-IV (Medicinal Chemistry)3. Department of Pharmacognosy• Pharmacognosy-I• Pharmacognosy-II4. Department of Pharmacology• Physiology• Anatomy & Histology• Pathology91 | Pakistan Pharmacist Federation; www.pharmacistfed.pk,www.pharmafed.wordpress.com, www.pharmarev.com, info@pharmacistfed.pk,
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NATIONAL CURRICULUM REVISIONCOMMITT
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The aims and objectives of Doctor o
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14. To prepare pharmacy graduates f
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and its Applications in Pharmacy)[L
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DETAILS OF COURSES ( SEMESTER SYSTE
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PHARM 311 PHARMACEUTICS-I (Physical
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9. Naser-ud-Din, Introduction to St
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Expression of Genetic Information,
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2. STRUCTURE OF CELL: Cell Membrane
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Communications SkillsObjectives: En
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Experiments to demonstrate some of
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1990.9. Naser-ud-Din, Introduction
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Hemorrhage and Other Causes of Hypo
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IS 402ISLAMIC STUDIESCr. Hr.: 01 Ma
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Publications New Delhi (1989)9) Dr.
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PHARM 413 PHARMACEUTICS-V (Pharmace
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e. Drug treatment of chronic inflam
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j. Labiatae Peppermint, Thyme, Spea
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Page 43 and 44: i. Drugs used for cough (Anti-tussi
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Page 51 and 52: anaesthetic drugs on human and the
Page 53 and 54: 5. Plant SteroidsIntroduction, extr
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Page 59 and 60: of frog. To demonstrate the effects
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Page 65 and 66: 1. INTRODUCTION(a) Role of Pharmaci
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Page 71 and 72: 14. Ronald D Schoenwald, Pharmacoki
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Page 79 and 80: vaccines.5. MISCELLANEOUS DETERMINA
Page 81 and 82: 3. T V Ramabhadran, Pharmaceutical
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Page 95 and 96: Paper 4 Pharmacy Practice -VI (Fore
Page 97 and 98: 9. PREPARATION AND PROPERTIES OF HE
Page 99 and 100: c. Proteins and Amino acids: Brief
Page 101 and 102: 3. PHYSICO-CHEMICAL PRINCIPLES:a. S
Page 103 and 104: 2. Cooper and Gunns Tutorial Pharma
Page 105 and 106: Experiences, Motivation and Emotion
Page 107 and 108: 5. CENTRAL NERVOUS SYSTEM: Nerve Mu
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Page 111 and 112: 1. DESCRIPTION OF STATISTICS: Descr
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Page 115 and 116: 1. Writing. Advanced by Ron White.
Page 117 and 118: effervescent, granulated salts. Har
Page 119 and 120: Parasympathetic antagonists.f. Gang
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Page 123 and 124: Sources, structure, preparation, de
Page 125 and 126: Microbiology with special reference
Page 127 and 128: Objectives• Develop vision of his
Page 129 and 130: 2 To enhance understanding of the s
Page 131 and 132: 1) Basic Concepts of Islam & Scienc
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their identification. Isolation and
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6. ROLE OF PHARMACIST: As Public He
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d. I.R. Spectroscopye. Mass Spectro
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F O U R T H P R O F E S S I O N A L
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16. NUCLEAR PHARMACY.17. THE PHYSIC
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I. Ensure continuity of pharmaceuti
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1. MASS TRANSFER.2. HEAT TRANSFER.3
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Delhi, 1986.4. Remington’s Pharma
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14. IN-VITRO-IN-VIVO CORRELATION (I
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5. QUALITY CONTROL OF STERILE PRODU
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F I N A L P R O F E S S I O N A LPH
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3. Tyagi, Textbook of Synthetic Dru
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Horwood Publishing limited, West Su
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NOTE:- Practical of the subject sha
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3. The Pharmacy Act 1967.4. The Poi
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5. Application of Computers in Hosp
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