Download Pharmacy Curriculum Draft (NCRC); 2011

14. Ronald D Schoenwald, Pharmacokinetics in drug discovery andDevelopment, CRC Press LLC, USA, 2002.PHARM 618 PHARMACEUTICS-IX (Pharmaceutical QualityManagement-I) [Th.]Cr. Hr.: 03 Marks: 1001. INTRODUCTION:(a) Basic concepts about introduction of pharmaceutical industry inrelevance to quality assurance and quality control departments, testing,quality management system, quality assurance, quality control,Standard.(b) General understanding of good laboratory practices and validation2. QUALITY CONTROL OF SOLID DOSAGE FORMS:(a) Physical tests: Hardness, Thickness and Diameter, Friability,Disintegration, Weight Variation.(b)Chemical tests: Content uniformity, Assay of active ingredients anddissolution tests of Powders, Granules, Tablets and Capsules.3. QUALITY CONTROL OF SYRUPS AND ELIXIRS:Viscosity, itsdetermination and application in the Quality Control of Pharmaceuticals,Weight per ml and Assay of active ingredients.4. QUALITY CONTROL OF SUPPOSITORIES: Disintegration test,Uniformity of weight, Assay of active ingredients, Liquefaction time test andBreaking test.5. QUALITY CONTROL OF STERILE PRODUCTS(PARENTERALS):Sterility Test and Sterile section management, Leaker’stest, Clarity test, Pyrogen test for Parenteral and other sterile preparations,Assay for active ingredients.PHARM 619 PHARMACEUTICS-IX (Pharmaceutical QualityManagement-I) [Lab.]Cr. Hr.: 01 Marks: 50NOTE:-Practical of the subject shall be designed from time to time on the basis of theabove mentioned theoretical topics and availability of the facilities, e.g.Assay of various spirits, tinctures, extracts, syrups and elixirs, Assay ofOintments and suppositories, Assay of tablets and capsules, Test foralkalinity of glass, Determination of alcohol contents in thePharmaceutical preparations and Pyrogen test. Sterility test,71 | Pakistan Pharmacist Federation; www.pharmacistfed.pk,www.pharmafed.wordpress.com, www.pharmarev.com, info@pharmacistfed.pk,