WHO Drug Information Vol. 25, No. 2, 2011
WHO Drug Information Vol. 25, No. 2, 2011
WHO Drug Information Vol. 25, No. 2, 2011
You also want an ePaper? Increase the reach of your titles
YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.
Proposed INN: List 105 <strong>WHO</strong> <strong>Drug</strong> <strong>Information</strong> <strong>Vol</strong>. <strong>25</strong>, <strong>No</strong>. 2, <strong>2011</strong>upamostat4-{(2S)-3-{3-[(E)-N′-hidroxicarbamimidoil]fenil}-2-[2,3,5-tri(propan-2-il)bencenosulfonamido]propanoil}piperazina-1-carboxilato de etiloantineoplásicoC 32 H 47 N 5 O 6 S 1191101-18-4H 3 CCH 3OHNH 3 CCH 3OH 3 CO SCH 3NHO N O CHH3NNH 2Ovatelizumabum #vatelizumabvatélizumabvatelizumabimmunoglobulin G4-kappa, anti-[Homo sapiens ITGA2 (integrinalpha 2, CD49b, GPIa, subunit of the alpha2beta1 integrin (VLA-2,collagen receptor))], humanized monoclonal antibody;gamma4heavy chain (1-446) [humanized VH (Homo sapiens IGHV4-59*01(79.40%) -(IGHD)-IGHJ6*01) [8.7.13] (1-119) -Homo sapiensIGHG4*01 (120-446)], (133-213')-disulfide with kappa light chain(1'-213') [humanized V-KAPPA (Homo sapiens IGKV6D-41*01(77.90%) -IGKJ1*01) [5.3.9] (1'-106') -Homo sapiens IGKC*01 (107'-213')]; (2<strong>25</strong>-2<strong>25</strong>":228-228")-bisdisulfide dimerimmunomodulatorimmunoglobuline G4-kappa, anti-[Homo sapiens ITGA2 (intégrinealpha 2, CD49b, GPIa, sous-unité de l'intégrine alpha2bêta1 (VLA-2,récepteur du collagène))], anticorps monoclonal humanisé;chaîne lourde gamma4 (1-446) [VH humanisé (Homo sapiensIGHV4-59*01 (79.40%) -(IGHD)-IGHJ6*01) [8.7.13] (1-119) -Homosapiens IGHG4*01 (120-446)], (133-213')-disulfure avec la chaînelégère kappa (1'-213') [V-KAPPA humanisé (Homo sapiens IGKV6D-41*01 (77.90%) -IGKJ1*01) [5.3.9] (1'-106') -Homo sapiens IGKC*01(107'-213')]; dimère (2<strong>25</strong>-2<strong>25</strong>":228-228")-bisdisulfureimmunomodulateurinmunoglobulina G4-kappa, anti-[Homo sapiens ITGA2 (integrinaalfa 2, CD49b, GPIa, subunidad de la integrina alfa2beta1 (VLA-2,receptor del colageno))], anticuerpo monoclonal humanizado;cadena pesada gamma4 (1-446) [VH humanizada (Homo sapiensIGHV4-59*01 (79.40%) -(IGHD)-IGHJ6*01) [8.7.13] (1-119) -Homosapiens IGHG4*01 (120-446)], (133-213')-disulfuro con la cadenaligera kappa (1'-213') [V-KAPPA humanizada (Homo sapiensIGKV6D-41*01 (77.90%) -IGKJ1*01) [5.3.9] (1'-106') -Homo sapiensIGKC*01 (107'-213')]; dímero (2<strong>25</strong>-2<strong>25</strong>":228-228")-bisdisulfuroinmunomodulador198
Change language