WHO Drug Information Vol. 25, No. 2, 2011

Proposed INN: List 105 WHO Drug Information Vol. 25, No. 2, 2011lurbinectédinelurbinectedinaacétate de (1'R,6R,6aR,7R,13S,14S,16R)-8,14-dihydroxy-6',9-diméthoxy-4,10,23-triméthyl-19-oxo-2',3',4',6,7,9',12,13,14,16-décahydro-6aH-spiro[7,13-azano-6,16-(épithiopropanooxyméthano)[1,3]dioxolo[7,8]isoquinolino[3,2-b][3]benzazocine-20,1'-pyrido[3,4-b]indol]-5-ylantinéoplasiqueacetato de (1′R,6R,6aR,7R,13S,14S,16R)-8,14-dihidroxi-6′,9-dimetoxi-4,10,23-trimetil-19-oxo-2',3',4',6,7,9',12,13,14,16-decahidro-16H-spiro[7,13-azano-6,16-(epitiopropanooximetano)[1,3]dioxolo[7,8]isoquinolino[3,2-b][3]benzazocina-20,1′-pirido[3,4-b]indol]-5-iloantineoplásicoC 41 H 44 N 4 O 10 S 497871-47-3HHOHONHOOH 3 CNH 3 COHHOHNHHSONHOCH 3CH 3OCH 3H 3 COmelphalanum flufenamidummelphalan flufenamidemelphalan flufénamidemelfalán flufenamidaethyl (2S)-2-[(2S)-2-amino-3-{4-[bis(2-chloroethyl)amino]phenyl}propanamido]-3-(4-fluorophenyl)propanoatealkylating agent(2S)-2-[(2S)-2-amino-3-{4-[bis(2-chloroéthyl)amino]phényl}propanamido]-3-(4-fluorophényl)propanoate d'éthyleagent alkylant(2S)-2-[(2S)-2-amino-3-{4-[bis(2-cloroetil)amino]fenil}propanamido]-3-(4-fluorofenil)propanoato de etiloagente alquilizanteC 24 H 30 Cl 2 FN 3 O 3 380449-51-4ClClNHNH 2HNOHOO CH 3F180