WHO Drug Information Vol. 25, No. 2, 2011
WHO Drug Information Vol. 25, No. 2, 2011
WHO Drug Information Vol. 25, No. 2, 2011
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<strong>WHO</strong> <strong>Drug</strong> <strong>Information</strong> <strong>Vol</strong>. <strong>25</strong>, <strong>No</strong>. 2, <strong>2011</strong> Proposed INN: List 105simeprevirumsimeprevirsiméprévirsimeprevir(2R,3aR,10Z,11aS,12aR,14aR)-N-(cyclopropanesulfonyl)-2-({7-methoxy-8-methyl-2-[4-(propan-2-yl)-1,3-thiazol-2-yl]quinolin-4-yl}oxy)-5-methyl-4,14-dioxo-2,3,3a,4,5,6,7,8,9,11a,12,13,14,14a-tetradecahydrocyclopenta[c]cyclopropa[g][1,6]diazacyclotetradecine-12a(1H)-carboxamideantiviral(2R,3aR,10Z,11aS,12aR,14aR)-N-(cyclopropanesulfonyl)-2-({7-méthoxy-8-méthyl-2-[4-(propan-2-yl)-1,3-thiazol-2-yl]quinoléin-4-yl}oxy)-5-méthyl-4,14-dioxo-2,3,3a,4,5,6,7,8,9,11a,12,13,14,14a-tétradécahydrocyclopenta[c]cyclopropa[g][1,6]diazacyclotétradécine-12a(1H)-carboxamideantiviral(2R,3aR,10Z,11aS,12aR,14aR)-N-(ciclopropanosulfonil)-2-({7-metoxi-8-metil-2-[4-(propan-2-il)-1,3-tiazol-2-il]quinolin-4-il}oxi)-5-metil-4,14-dioxo-2,3,3a,4,5,6,7,8,9,11a,12,13,14,14a-tetradecahidrociclopenta[c]ciclopropa[g][1,6]diazaciclotetradecina-12a(1H)-carboxamidaantiviralC 38 H 47 N 5 O 7 S 2 923604-59-5OHOO SNHONHHHHOOCH 3CH 3NNCH 3S CH 3NOCH 3siponimodumsiponimodsiponimodsiponimod1-({4-[(1E)-1-({[4-cyclohexyl-3-(trifluoromethyl)phenyl]methoxy}imino)ethyl]-2-ethylphenyl}methyl)azetidine-3-carboxylic acidimmunomodulatoracide 1-({4-[(1E)-1-({[4-cyclohexyl-3-(trifluorométhyl)phényl]méthoxy}imino)éthyl]-2-éthylphényl}méthyl)azétidine-3-carboxyliqueimmunomodulateurácido 1-({4-[(1E)-1-({[4-ciclohexil-3-(trifluorometil)fenil]metoxi}imino)etil]-2-etilfenil}metil)azetidina-3-carboxílicoinmunomoduladorC 29 H 35 F 3 N 2 O 3 1230487-85-0NONCO 2 HCF 3CH 3CH 3193
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