WHO Drug Information Vol. 25, No. 2, 2011

WHO Drug Information Vol. 25, No. 2, 2011 Proposed INN: List 105pegnivacoginaaptámero de ácido ribomucléico que se une a Factor XIa;éster of 2'-O-metil-5'-O-fosfonoguanilil-(3'→5')-2'-O-metiluridilil-(3'→5')-2'-O-metilguanilil-(3'→5')-2'-O-metilguanilil-(3'→5')-2'-O-metiladenilil-(3'→5')-2'-desoxi-2'-fluorocitidilil-(3'→5')-2'-desoxi-2'-fluorouridilil-(3'→5')-2'-O-metiladenilil-(3'→5')-2'-desoxi-2'-fluorouridilil-(3'→5')-2'-O-metiladenilil-(3'→5')-2'-desoxi-2'-fluorocitidilil-(3'→5')-2'-desoxi-2'-fluorocitidilil-(3'→5')-2'-Ometilguanilil-(3'→5')-2'-desoxi-2'-fluorocitidilil-(3'→5')-2'-Ometilguanilil-(3'→5')-2'-desoxi-2'-fluorouridilil-(3'→5')-2'-Ometiladenilil-(3'→5')-2'-O-metiladenilil-(3'→5')-2'-desoxi-2'-fluorouridilil-(3'→5')-2'-O-metilguanilil-(3'→5')-2'-desoxi-2'-fluorocitidilil-(3'→5')-2'-O-metiluridilil-(3'→5')-guanilil-(3'→5')-2'-O-metilcitidilil-(3'→5')-2'-desoxi-2'-fluorocitidilil-(3'→5')-2'-desoxi-2'-fluorouridilil-(3'→5')-2'-O-metilcitidilil-(3'→5')-2'-O-metilcitidilil-(3'→5')-2'-O-metiladenilil-(3'→5')-2'-O-metilcitidilil-(3'→3')-timidina6-[(2,6-bis{N-[ω-metoxipoli(oxietileno)carbonil]}-L-lisil)amino]hexan-1-olanticoagulanteC 327 H 422 F 11 N 114 O 213 P 31 (C 2 H 4 O) n 959716-28-0(3'-5')-R-pmG-mU-mG-mG-mA-dflC-dflU-mA-dflU-mA-dflC-dflC-mGdflC-mG-dflU-mA-mA-dflU-mG-dflC-mU-G-mC-dflC-dflU-mC-mC-mA-mC3'-3'dTLegend:dfl = 2'-deoxy-2'-fluoro ; m = 2'-O-methyl ; p (as prefix) = 5'-phosphateR- =OON OCH3x + y = nHyOH 3 C O H HN CH2O Nx HOpictrelisibumpictrelisibpictrélisibpictrelisib2-{1H-indazol-4-yl}-6-{[4-(methanesulfonyl)piperazin-1-yl]methyl}-4-(morpholin-4-yl)thieno[3,2-d]pyrimidineantineoplastic2-(1H-indazol-4-yl)-6-{[4-(méthanesulfonyl)pipérazin-1-yl]méthyl}-4-(morpholin-4-yl)-thiéno[3,2-d]pyrimidineantinéoplasique2-{1H-indazol-4-il}-6-{[4-(metanosulfonil)piperazin-1-il]metil}-4-(morfolin-4-il)tieno[3,2-d]pirimidinaantineoplásicoC 23 H 27 N 7 O 3 S 2 957054-30-7OHNNNNOONSNN S CH 3189