WHO Drug Information Vol. 24, No. 4, 2010
WHO Drug Information Vol. 24, No. 4, 2010
WHO Drug Information Vol. 24, No. 4, 2010
You also want an ePaper? Increase the reach of your titles
YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.
<strong>WHO</strong> <strong>Drug</strong> <strong>Information</strong>, <strong>Vol</strong>. <strong>24</strong>, <strong>No</strong>. 4, <strong>2010</strong> Proposed INN: List 104enavatuzumabum #enavatuzumabénavatuzumabenavatuzumabimmunoglobulin G1-kappa, anti-[Homo sapiens TNFRSF12A (tumornecrosis factor receptor superfamily member 12A, fibroblast growthfactor (FGF)-inducible 14 kDa protein, Fn14, TNF-like weak inducerof apoptosis (Tweak) receptor, Tweak receptor, TweakR, CD266],humanized monoclonal antibody;gamma1 heavy chain (1-449) [humanized VH (Homo sapiensIGHV3-7*01 (86.70%) -(IGHD)-IGHJ6*01 T123>L (114)) [8.10.10] (1-119) -Homo sapiens IGHG1*01 CH3 D12>E (358), L14>M (360)(120-449)], (222-218')-disulfide with kappa light chain (1'-218')[humanized V-KAPPA (Homo sapiens IGKV1-39*01 (84.80%) -IGKJ4*01) [10.3.9] (1'-111') -Homo sapiens IGKC*01 (112'-218')];(228-228":231-231")-bisdisulfide dimerantineoplasticimmunoglobuline G1-kappa, anti-[Homo sapiens TNFRSF12A(membre 12A de la superfamille des récepteurs du facteur denécrose tumorale, protéine de 14 kDa induite par le facteur decroissance du fibroblaste (FGF), Fn14, TNF-like faible inducteurd'apoptose (Tweak), récepteur de Tweak, CD266], anticorpsmonoclonal humanisé;chaîne lourde gamma1 (1-449) [VH humanisé (Homo sapiensIGHV3-7*01 (86.70%) -(IGHD)-IGHJ6*01 T123>L (114)) [8.10.10] (1-119) -Homo sapiens IGHG1*01 CH3 D12>E (358), L14>M (360)(120-449)], (222-218')-disulfure avec la chaîne légère kappa (1'-218')[V-KAPPA humanisé (Homo sapiens IGKV1-39*01 (84.80%) -IGKJ4*01) [10.3.9] (1'-111') -Homo sapiens IGKC*01 (112'-218')];dimère (228-228":231-231")-bisdisulfureantinéoplasiqueinmunoglobulina G1-kappa, anti-[TNFRSF12A de Homo sapiens(miembro 12A de la superfamilia de receptores del factor denecrosis tumoral, proteína de 14 kDa inducida por el factor decrecimiento de fibroblastos (FGF), Fn14, TNF-like débil inductor deapoptosis (Tweak), receptor de Tweak, CD266], anticuerpomonoclonal humanizado;cadena pesada gamma1 (1-449) [VH humanizada (Homo sapiensIGHV3-7*01 (86.70%) -(IGHD)-IGHJ6*01 T123>L (114)) [8.10.10] (1-119) -Homo sapiens IGHG1*01 CH3 D12>E (358), L14>M (360)(120-449)], (222-218')-disulfuro con la cadena ligera kappa (1'-218')[V-KAPPA humanizada (Homo sapiens IGKV1-39*01 (84.80%) -IGKJ4*01) [10.3.9] (1'-111') -Homo sapiens IGKC*01 (112'-218')];dímero (228-228":231-231")-bisdisulfuroantineoplásico367
Change language