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WHO Drug Information Vol. 24, No. 4, 2010

WHO Drug Information Vol. 24, No. 4, 2010

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<strong>WHO</strong> <strong>Drug</strong> <strong>Information</strong>, <strong>Vol</strong>. <strong>24</strong>, <strong>No</strong>. 4, <strong>2010</strong> Proposed INN: List 104granotapidumgranotapidegranotapidegranotapidadiethyl 2-({2-[3-(dimethylcarbamoyl)-4-{4'-(trifluoromethyl)-[1,1'-biphenyl]-2-carboxamido}phenyl]acetyloxy}methyl)-2-phenylpropanedioateantihyperlipidaemic2-[({2-[3-(diméthylcarbamoyl)-4-({[4'-(trifluorométhyl)-[1,1'-biphényl]-2-yl-carboxamido)phényl]acétyl}oxy)méthyl]-2-phénylpropanedioatede diéthyleantihyperlipidémiant2-({2-[3-(dimetilcarbamoil)-4-{4'-(trifluorometil)-[1,1'-bifenil]-2-carboxamido}fenil]acetiloxi}metil)-2-fenilpropanodioato de dietiloantihiperlipémicoC 39 H 37 F 3 N 2 O 8 594842-13-4CF 3H 3 COOCH 3OOOOONHONCH 3CH 3icrucumabum #icrucumabicrucumabimmunoglobulin G1-kappa, anti-[Homo sapiens FLT1 (fms-relatedtyrosine kinase 1, vascular endothelial growth factor receptor 1,VEGFR-1, VEGFR, FLT, FRT, vascular permeability factorreceptor)], Homo sapiens monoclonal antibody;gamma1 heavy chain (1-456) [Homo sapiens VH (IGHV3-33*01(93.90%) -(IGHD)-IGHJ6*01 [8.8.19] (1-126) -IGHG1*03 (127-456)],(229-215')-disulfide with kappa light chain (1'-215') [Homo sapiens V-KAPPA (IGKV3-20*01 (100.00%) -IGKJ4*01) [7.3.9] (1'-108') -IGKC1*01 (109'-215')]; (235-235'':238-238'')-bisdisulfide dimerantineoplasticimmunoglobuline G1 kappa, anti-[Homo sapiens FLT1 (tyrosinekinase 1 apparentée au fms, récepteur 1 du facteur de croissanceendothélial vasculaire, VEGFR-1, VEGFR, FLT, FRT, récepteur dufacteur de perméabilité vasculaire)], Homo sapiens anticorpsmonoclonal;chaîne lourde gamma1 (1-456) [Homo sapiens VH (IGHV3-33*01(93.90%) -(IGHD)-IGHJ6*01 [8.8.19] (1-126) -IGHG1*03 (127-456)],(229-215')-disulfure avec la chaîne légère kappa (1'-215') [Homosapiens V-KAPPA (IGKV3-20*01 (100.00%) -IGKJ4*01) [7.3.9] (1'-108') -IGKC1*01 (109'-215')]; dimère (235-235'':238-238'')-bisdisulfureantinéoplasique375

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