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Master the board step 3

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<strong>Master</strong> <strong>the</strong> Boards: USMLE Step 3<br />

Basic Science Correlate<br />

Mechanism of Calcium Blockers: Why They Don’t Work in PAD<br />

Beta blockers are not<br />

contraindicated with PAD.<br />

If <strong>the</strong> patient needs <strong>the</strong>m<br />

for ischemic disease, <strong>the</strong>y<br />

should be used.<br />

In PAD, <strong>the</strong> a<strong>the</strong>rosclerotic obstruction is on <strong>the</strong> inside <strong>the</strong> vessel. Calcium<br />

blockers dilate <strong>the</strong> muscular layer, which is exterior to <strong>the</strong> a<strong>the</strong>rosclerosis in<br />

<strong>the</strong> center. Dilating <strong>the</strong> outer layer does not expand <strong>the</strong> inside.<br />

CCS Tip: On CCS, move <strong>the</strong> clock forward several weeks. PAD is not an emergency!<br />

If initial <strong>the</strong>rapies do not work and <strong>the</strong> pain progresses, or <strong>the</strong>re are signs of<br />

ischemia such as gangrene or pain at rest, <strong>the</strong>n perform surgical bypass.<br />

Rhythm Disorders<br />

Atrial Fibrillation (A-Fib)<br />

A-fib presents with palpitations and an irregular pulse in a person with a<br />

history of hypertension, ischemia, or cardiomyopathy.<br />

Diagnostic Testing<br />

If <strong>the</strong> initial EKG does not show <strong>the</strong> answer, a patient in <strong>the</strong> hospital should<br />

be placed on telemetry monitoring. Outpatients who are hemodynamically<br />

stable should undergo Holter monitoring, which is continuous, ambulatory<br />

cardiac rhythm monitoring for 24 hours or longer.<br />

CCS Tip: For CCS cases, o<strong>the</strong>r tests to order once A-fib is found on EKG are <strong>the</strong><br />

following:<br />

CHADS<br />

C = CHF<br />

H = Hypertension<br />

A = Age > 75<br />

D = Diabetes<br />

S = Stroke or TIA<br />

CHADS score of 0 – 1<br />

needs aspirin. At 2 or<br />

more, use warfarin,<br />

dabigatran, rivaroxaban, or<br />

apixaban.<br />

··<br />

Echocardiography: Looking for clots, valve function, and left atrial size<br />

··<br />

Thyroid function testing: T4 and TSH levels<br />

··<br />

Electrolytes: Potassium, magnesium, and calcium levels<br />

··<br />

Troponin or CK-MB levels: These may be appropriate to test in some<br />

acute-onset cases.<br />

Treatment<br />

Unstable patients should undergo immediate synchronized electrical cardioversion.<br />

Unstable patients should be cardioverted with <strong>the</strong> first screen, without<br />

waiting for TEE or anticoagulation with heparin or warfarin. Instability is<br />

defined as a systolic blood pressure < 90, congestive failure, confusion related<br />

to hemodynamic instability, or chest pain.<br />

Stable patients should have <strong>the</strong>ir ventricular heart rate slowed if it is > 100–110<br />

per minute.<br />

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