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Rheumatology<br />

Fibromyalgia Trigger Points<br />

Treatment<br />

Treat symptoms with <strong>the</strong> following:<br />

··<br />

Exercise<br />

··<br />

Milnacipran, duloxetine, or pregabalin (<strong>the</strong> best initial <strong>the</strong>rapy)<br />

··<br />

Tricyclic antidepressants, such as amitriptyline, are effective but have more<br />

adverse effects.<br />

NSAIDs are not first line for<br />

fibromyalgia.<br />

Polymyalgia Rheumatica (PMR)<br />

Presents with a person > 50 years old with profound pain and stiffness of <strong>the</strong><br />

proximal muscles, such as shoulders and pelvic girdle. The stiffness is worse<br />

in <strong>the</strong> morning and is localized to <strong>the</strong> muscles ra<strong>the</strong>r than to <strong>the</strong> joints. The<br />

ESR is elevated, and <strong>the</strong>re is an amazing response to steroids.<br />

Pain is much more<br />

prominent than weakness<br />

in PMR.<br />

Nonspecific features of PMR are <strong>the</strong> following:<br />

··<br />

Fever, weight loss, and malaise<br />

··<br />

Normocytic anemia<br />

··<br />

Normal CPK, EMG, aldolase, and muscle biopsy<br />

··<br />

No muscle atrophy<br />

• Age > 50 + Proximal<br />

muscle pain + ↑ESR =<br />

PMR<br />

The following table compares chronic fatigue syndrome, fibromyalgia, and<br />

polymyalgia rheumatica.<br />

149

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