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Cardiology<br />

When is <strong>the</strong> goal of <strong>the</strong>rapy an LDL < 70?<br />

a. CHF<br />

b. Diabetes<br />

c. Coronary disease and carotid disease<br />

d. Coronary disease and diabetes<br />

e. Diabetes and hypertension<br />

Step 3 will only ask clear<br />

questions on lipids.<br />

Answer: D. The goal of LDL can be < 70 for patients at <strong>the</strong> very highest risk of infarction.<br />

This includes those with acute coronary syndromes or <strong>the</strong> combination of coronary<br />

disease and a very severe risk factor, such as diabetes.<br />

The most common adverse effect of statin medications is liver toxicity.<br />

As many as 1 percent of patients will stop a statin because of its effect on<br />

raising transaminases. Liver function tests should be routinely checked.<br />

Rhabdomyolysis is not <strong>the</strong> most common adverse effect. There is no routine<br />

indication to check CPK levels.<br />

Sex and <strong>the</strong> Heart<br />

A man develops erectile dysfunction after an infarction. What is <strong>the</strong> most common<br />

cause?<br />

a. Metoprolol<br />

b. Nitrates<br />

c. ACE inhibitors<br />

d. Aspirin<br />

e. Anxiety<br />

Answer: E. Anxiety is <strong>the</strong> most common cause of erectile dysfunction postinfarction.<br />

Although beta blockers may be <strong>the</strong> most common medication associated with erectile<br />

dysfunction, anxiety is still a more common cause of erectile dysfunction than beta<br />

blockers.<br />

A man develops erectile dysfunction postinfarction. You are planning to start<br />

sildenafil. Which of <strong>the</strong> following medications must you stop?<br />

a. Metoprolol<br />

b. Nitrates<br />

c. ACE inhibitors<br />

d. Aspirin<br />

Answer: B. Nitrates are contraindicated when medications such as sildenafil are to be<br />

used. When used at <strong>the</strong> same time, <strong>the</strong>y can cause a dangerous level of hypotension.<br />

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