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Pediatrics<br />

Breastfeeding<br />

The advantages of breastfeeding:<br />

··<br />

Passive transfer of T-cell immunity: Decreased risk of allergies and gastrointestinal<br />

and respiratory infections<br />

··<br />

Psychological/emotional: Maternal-infant bonding<br />

Basic Science Correlate<br />

••<br />

IgM is secreted during early stages of humoral immunity. It is <strong>the</strong> first<br />

antibody secreted.<br />

••<br />

IgG causes sustained immunity to pathogens. It is <strong>the</strong> only immunoglobulin<br />

that crosses <strong>the</strong> placenta.<br />

••<br />

IgE binds to allergens and secretes histamine.<br />

••<br />

IgA is found in mucosal areas (intestines, saliva, tears, breast milk). It is<br />

secreted during breastfeeding.<br />

Monomer<br />

IgD, IgE, IgG<br />

Dimer<br />

IgA<br />

Pentamer<br />

IgM<br />

Following are <strong>the</strong> contraindications to breastfeeding:<br />

··<br />

Galactosemia in baby<br />

··<br />

HIV<br />

··<br />

HSV if lesions on breast<br />

··<br />

Acute maternal disease if absent in infant (e.g., tuberculosis, sepsis)<br />

··<br />

Maternal cancer receiving treatment<br />

··<br />

Substance abuse<br />

Breastfeeding is not<br />

contraindicated in mastitis.<br />

375

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