Master the board step 3

Section 5
Pediatrics
contributing author Elizabeth August, MD
The Newborn
Management of the Newborn
At delivery, give the following:
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0.5 percent erythromycin ophthalmic ointment
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1 mg of vitamin K IM to prevent hemorrhagic disease
Basic Science Correlate
••
Erythromycin is a bacteriostatic drug. Bacteriostatic drugs inhibit
reproduction of the bacteria by blocking ribosomal formation of proteins.
••
Penicillins are bactericidal. Bactericidal antibiotics kill bacteria by cell wall
inhibition.
Basic Science Correlate
Factors II, VII, IX, and X are vitamin K–dependent clotting factors. Proteins
C and S are vitamin K–dependent anticoagulants. Vitamin K adds a carboxyl
group onto the glutamic acid on these factors. Protein C inhibits factor V.
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