Master the board step 3

Master the Boards: USMLE Step 3
Arteriosclerotic Occlusive Disease of the Lower Extremities
The classic presentation of this condition is pain in the legs on exercise that is
relieved by rest (intermittent claudication).
If the claudication does not interfere significantly with the patient’s lifestyle, no
workup is indicated. The only management indicated is
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cessation of smoking and
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the use of cilostazol and aspirin.
Basic Science Correlate
Cilostazol is a selective inhibitor of phosphodiesterase 3 (PDE3).
If the pain is more severe, diagnosis is with the following:
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Doppler studies looking for a pressure gradient (ankle-brachial index [ABI]