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<strong>Undergrad</strong>uate Research at UMass Dartmouth<br />
There was a trend for higher indentation distance (represnting weaker mechanical properties) and significantly more crosslinks in<br />
the ribose treated group (R) compared to vehicle controls (VEH)<br />
109<br />
we would like to carry out bending tests because<br />
they will give a more complete understanding of<br />
how the mechanical properties of samples change<br />
after incubation. We also plan on measuring specific<br />
AGEs, such as pentosidine, in our assays so that we<br />
can analyze the exact AGE chemical structures that<br />
are forming. Lastly, we hope to apply imaging techniques<br />
such as microCT analysis in order to measure<br />
microdamage in samples. A long-term goal for this<br />
project is to utilize our accumulated understanding<br />
of Vitamin B6 on the inhibition of AGEs in vitro to<br />
establish reason for animal model testing.<br />
From this experience, I have learned that research<br />
Samples treated with ribose had a lower elastic modulus (measure of stiffness) compared to the control group. This trend was seen<br />
across all age groups (57-87 years)
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