Create successful ePaper yourself
Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.
SZENT-GYÖRGYI STUDENTS<br />
ROLAND FEJES<br />
Szeged Scientists Academy, 4 th year<br />
University of Szeged,<br />
Faculty of Medicine, 4 th year<br />
YEAR OF BIRTH:<br />
<strong>19</strong>97<br />
FORMER<br />
SZENT-GYÖRGYI<br />
PUPIL:<br />
yes<br />
SZENT-GYÖRGYI<br />
MENTOR:<br />
József Kaszaki<br />
JUNIOR MENTOR<br />
Szabolcs Péter Tallósy<br />
SPECIALIZATION:<br />
Pathophysiology of<br />
circulation, sepsis<br />
SECONDARY<br />
SCHOOL:<br />
Radnóti Miklós<br />
Experimental Grammar<br />
School, Szeged<br />
NAME OF TEACHER:<br />
Béla Gál<br />
LANGUAGES:<br />
IMPORTANCE, AIMS AND POSSIBLE OUTCOME OF RESEARCH<br />
Sepsis is one of the biggest challenges in medicine because of its rapidly proliferating<br />
nature. On account of the complexity of its pathomechanism, sepsis is hard to diagnose,<br />
and amongst the countless therapeutic possibilities used, there is no perfect solution yet.<br />
A common feature of septic multiorgan failure (MOF) is microcirculatory dysfunction,<br />
which leads to tissue hypoperfusion, mitochondrial dysfunction and necrosis. Thus,<br />
microcirculatory-mitochondrial resuscitation seems to be a promising therapeutic target.<br />
In our previous studies we have shown that the selective modulation of the endothelin-1<br />
(ET-1) receptors – the most potent vasoactive agent of the body – can be a therapeutic<br />
solution for sepsis on macrohemodynamics, microcirculation and mitochondrial<br />
respiration too. Nevertheless, it is unknown if the proven mechanism is a direct or indirect<br />
effect on mitochondria and if it has any advantages compared to the today used inotropic<br />
therapies.<br />
AMBITIONS AND CAREER GOALS<br />
In this project my first goal is to learn in vivo techniques which I can perform on rodents<br />
and minipigs. I am interested in the technique of high-resolution respirometry (Oroboros<br />
O2k), which is a useful tool to investigate mitochondrial functions. I would like to expand<br />
both my theoretical and practical knowledge, which I will be able to use either in medical<br />
research or in medical practice.<br />
HONORS AND PRIZES<br />
• 54 th Congress of European Society of Surgical Research, Geneva: Walter Brendel Award<br />
(20<strong>19</strong>)<br />
• Scholarship of New National Excellence Program <strong>2018</strong>/20<strong>19</strong><br />
• Student Scientific Conference, Pharmacology section: 1 st prize (<strong>2018</strong>)<br />
• Student Scientific Conference, Pharmacology section: 1 st prize (2017)<br />
• Student Scientific Conference, Operative Research section: 3 rd prize (2017)<br />
PUBLICATIONS<br />
–<br />
German/advanced<br />
English/intermediate<br />
102
Change language