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SZENT-GYÖRGYI STUDENTS<br />
LEÓ ASZTALOS<br />
Szeged Scientists Academy, 2 nd year<br />
University of Szeged,<br />
Faculty of Faculty of Medicine, 3 rd year<br />
YEAR OF BIRTH:<br />
<strong>19</strong>97<br />
FORMER<br />
SZENT-GYÖRGYI<br />
PUPIL:<br />
no<br />
SZENT-GYÖRGYI<br />
MENTOR:<br />
Lajos Kemény<br />
SPECIALIZATION:<br />
dermatology, immunology,<br />
bioinformatics<br />
SECONDARY SCHOOL:<br />
Zrenjaninska Gimnazija<br />
(Zrenjanin High School)<br />
NAME OF TEACHER:<br />
Angéla Lázár<br />
LANGUAGES:<br />
English/advanced<br />
German/intermediate<br />
Serbian/native speaker<br />
IMPORTANCE, AIMS AND POSSIBLE OUTCOME OF RESEARCH<br />
In our research, we are currently looking for correlations between the immune recognition<br />
of cancer patients and their response to treatments. Human leukocyte antigen (HLA)<br />
molecules are outstandingly important in adaptive immunity. These molecules show an<br />
exceptional variability, and the different variants can bind a different number of proteinsequences<br />
(i.e. different promiscuity). We hypothesize that HLA promiscuity has an effect<br />
on response to cancer immunotherapy, and thus could be an important biomarker. In<br />
addition to immunotherapy, we also investigate the relation between promiscuity and<br />
susceptibility to tumours, autoimmune and infectious diseases. In our laboratory, we<br />
analyse large and reliable databases which contain information about thousands of<br />
patients. We use up-to-date bioinformatic methods for the statistical analysis of these<br />
data.<br />
AMBITIONS AND CAREER GOALS<br />
As a medical student, what I find immensely important is having the most up-to- date<br />
information in the field of medicine. The Szent-Györgyi Programme is a great opportunity<br />
for me to acquire a deeper insight into the latest research, while also learning to make use<br />
of scientific literature and improving my problem solving ability through research work.<br />
Additionally, my work can contribute to a deeper understanding of pathophysiological<br />
processes and to choosing the most appropriate way of treating them.<br />
HONORS AND PRIZES<br />
• <strong>2018</strong> Scientific Student’s conference in Szeged, 2nd prize, Cellular biologyimmunology<br />
• XXIV. Korányi Frigyes Scientific Forum, 3rd prize, Experimental and clinical<br />
immunology - microbiology - genetics<br />
PUBLICATIONS<br />
–<br />
98
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