You also want an ePaper? Increase the reach of your titles
YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.
SZENT-GYÖRGYI STUDENTS<br />
VALÉRIA ÉVA MESZLÉNYI<br />
Szeged Scientists Academy, 3 rd year<br />
University of Szeged,<br />
Faculty of Medicine, 4 th year<br />
YEAR OF BIRTH:<br />
<strong>19</strong>96<br />
FORMER<br />
SZENT-GYÖRGYI<br />
PUPIL:<br />
no<br />
SZENT-GYÖRGYI<br />
MENTOR:<br />
László Siklós<br />
SPECIALIZATION:<br />
neuroscience<br />
SECONDARY<br />
SCHOOL:<br />
Petőfi Sándor Secondary<br />
School, Bonyhád<br />
NAME OF TEACHER:<br />
Andrea Nagy<br />
LANGUAGES:<br />
English/intermediate<br />
German/intermediate<br />
IMPORTANCE, AIMS AND POSSIBLE OUTCOME OF RESEARCH<br />
Our research unit is devoted to study the operation of the nervous system in physiological<br />
and pathological conditions. There are many neurodegenerative diseases, however, we<br />
focus on the amyotrophic lateral sclerosis which is the most common degenerative<br />
disease of the motor neuron system.<br />
Our main goal is to understand the complex mechanism and consequences of the<br />
disease furthermore to find possible therapeutic approaches. In our current experiments<br />
we would like to investigate the changes in communication of motor neurons and their<br />
neighboring non-neuronal cells in their natural environment with the acute and chronic<br />
neurodegenerative animal models in vivo. From methodological point of view we rely<br />
on geometrical statistically derived biologically relevant three-dimensional parameters<br />
acquired by basic structural investigations (light, fluorescent, and electron microscopic<br />
techniques), and biological structural research, labeling techniques for molecular imaging.<br />
AMBITIONS AND CAREER GOALS<br />
In the course of my scientific career I would like to study and understand the primary factors<br />
leading to the wide spectra of neurodegeneration and pathomechanisms of neuronal<br />
death. My aim is to accumulate proper knowledge that can serve the human society and<br />
medical science. I hope it will give me a possibility to contribute to development of novel<br />
therapeutic approaches.<br />
HONORS AND PRIZES<br />
• <strong>2018</strong>-20<strong>19</strong> New National Excellence Program Scholarship<br />
• <strong>2018</strong>-20<strong>19</strong> National Higher Educational Scholarship<br />
PUBLICATIONS<br />
Patai, R., Nógrádi, B., Meszlényi, V., Obál, I., Engelhardt, J.I., Siklós, L. (2017) Az amiotrófiás<br />
laterálszklerózis patofiziológiai tényezőinek központi kapcsolóeleme, a kalcium. Ideggy<br />
Szle 70(7- 8): 247-257.<br />
Meszlényi, V., Patai, R., Nógrádi, B., Engelhardt, J.I., Siklós, L. (2017) Commentary: Calcium<br />
in the pathomechanism of amyotrophic lateral sclerosis - Taking center stage? J Neurol<br />
Neuromed 2(4): 1-4.<br />
Obál, I. Nógrádi, B., Meszlényi, V., Patai, R., Ricken, G., Kovacs G.G., Tripolszki, K., Széll, M.,<br />
Siklós, L., Engelhardt, J.I. (20<strong>19</strong>) Experimental motor neuron disease induced in mice with<br />
long-term repeated intraperitoneal injections of serum from ALS patients. Int J Mol Sci<br />
(under review)<br />
120
Change language