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SzSA YearBook 2018/19

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SZENT-GYÖRGYI JUNIOR MENTORS<br />

GERGELY FODOR<br />

University of Szeged<br />

Department of Medical Physics and Informatics<br />

Cardiopulmonary Research Group<br />

Address: Korányi fasor 9, H-6720 Szeged, Hungary<br />

RESEARCH AREA<br />

Changes of the cardiovascular system also affect the<br />

respiratory system via heart-lung interactions. Our<br />

research group aims at characterizing mechanical and<br />

functional parameters of the respiratory system both in<br />

animal models and human subjects. Our research area<br />

includes the investigation of respiratory effects of various<br />

diseases (e.g. diabetes mellitus), interventions (e.g. blood<br />

loss or cardiopulmonary bypass), or drugs affecting the<br />

cardiovascular system or other, primarily respiratory<br />

diseases. Our research has a focus on the investigation of<br />

the respiratory effects of various, anaesthesia-related drugs,<br />

interventions, diseases. Our methods include a unique<br />

characterization of respiratory mechanical parameters<br />

with the use of the forced oscillation technique and<br />

measurement of partial pressure of exhaled carbon-dioxide<br />

(capnography).<br />

TECHNIQUES AVAILABLE IN THE LAB<br />

Participation in animal experiments, surgical methods,<br />

performing measurements and analysis of respiratory<br />

mechanical parameters, recording and analysis of vital<br />

parameters. Data analysis methods (R programming<br />

language), statistical analysis of data. Students can also<br />

participate in human experiments of the research group.<br />

SELECTED PUBLICATIONS<br />

Fodor, G.H., Babik, B., Czovek, D., Doras, C., Balogh, A.L.,<br />

Bayat, S., Habre, W., Petak, F. (2016) Fluid replacement and<br />

respiratory function: comparison of whole blood with<br />

colloid and crystalloid: a randomised animal study. Eur J<br />

Anaesthesiol 33:34-41<br />

Filep, A.*, Fodor, G.H.*, Kun-Szabo, F., Tiszlavicz, L., Razga, Z.,<br />

Bozso, G., Bozoki, Z., Szabo, G., Petak, F. (2016) Exposure to<br />

urban PM1 in rats: development of bronchial inflammation<br />

and airway hyperresponsiveness. Respir Res 17:26<br />

Fodor, G.H., Bayat, S., Babik, B., Habre, W., Peták, F. (<strong>2018</strong>)<br />

Reversing Cholinergic Bronchoconstriction by Common<br />

Inotropic Agents: A Randomized Experimental Trial on<br />

Isolated Perfused Rat Lungs. Anesth Analg 159(33):1335-<br />

1345<br />

Fodor, G.H., Balogh, A.L., Sudy, R., Ivankovits-Kiss, O., Babik, B.,<br />

Petak, F. (<strong>2018</strong>) Dopamine ameliorates bronchoconstriction<br />

induced by histaminergic and cholinergic pathways in<br />

rabbits. Respir Physiol Neurobiol 259: 156-161<br />

Balogh, A.L., Petak, F., Fodor, G.H., Tolnai, J., Csorba, Z., Babik,<br />

B. (2016) Capnogram slope and ventilation dead space<br />

parameters: comparison of mainstream and sidestream<br />

techniques. Br J Anaesth 117: 109-117<br />

78

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