Dominican Medicinal Plants: A Guide for Health Care Providers

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Activity/Effect Preparation Design & Model Results Reference Antibacterial Hexane, chloroform & methanol extracts of bark In vitro: against strains of 4 types of aerobic bacteria Hexane extract showed activity against E. coli & the methanol extract showed activity against Pseudomonas Camporese et al. 2003 Antibacterial Plant extract Screened in vitro against 5 enterobacteria pathogenic to humans Antidiabetic & hypoglycemic Bark decoction (water extract) In vivo; rabbit model Antioxidant Methanol & aqueous extract In vitro Antisecretory Bark extract In vitro: rabbit distal colon mounted in an Ussing chamber Antiviral REFERENCES Crude extract & fractions: aqueous & ethyl acetate In vitro: poliovirus 1 & bovine herpes virus 1; HEp-2 cultured cells aeruginosa Exhibited antibacterial activity against gastrointestinal pathogens Significantly decreased the hyperglycemic peak & the area under the glucose tolerance curve; results suggest effectiveness in diabetes mellitus control Showed radical scavenging activity Completely inhibited cholera toxin-induced chloride secretion if given prior to the toxin; adding after administration of the toxin had no effect on secretion; effect due to procyanidins Showed significant activity; ethyl acetate fraction inhibited replication by at least 99%; blocked the synthesis of viral antigens Caceres et al. 1990 Alarcon-Aguilara et al. 1998 Navarro et al. 2003 Hor et al. 1995 Felipe et al. 2006 Acevedo-Rodríguez, P. 1996. Flora of St. John, U.S. Virgin Islands. Memoirs of The New York Botanical Garden, Volume 78. Bronx, NY: NYBG Press. Alarcon-Aguilara FJ, Roman-Ramos R, Perez-Gutierrez S, Aguilar-Contreras A, Contreras-Weber CC, Flores-Saenz JL. 1998. Study of the anti-hyperglycemic effect of plants used as antidiabetics. Journal of Ethnopharmacology 61(2):101-10. Caballero-George C, Vanderheyden PM, Solis PN, Pieters L, Shahat AA, Gupta MP, Vauquelin G, Vlietinck AJ. 2001. Biological screening of selected medicinal Panamanian plants by radioligand-binding techniques. Phytomedicine 8(1):59-70. Caballero-George C, Vanderheyden PM, De Bruyne T, Shahat AA, Van den Heuvel H, Solis PN, Gupta MP, Claeys M, Pieters L, Vauquelin G, Vlietinck AJ. 2002. In vitro inhibition of [3H]-angiotensin II binding on the human AT1 receptor by proanthocyanidins from Guazuma ulmifolia bark. Planta Med 68(12):1066-71. Caceres A. 1996. as cited in Germosén-Robineau (2005). Plantas de uso medicinal en Guatemala. Guatemala, Guatemala: Editorial Univeresitaria de San Carlos. p. 126. 260
Caceres A, Cano O, Samayoa B, Aguilar L. 1990. Plants used in Guatemala for the treatment of gastrointestinal disorders. 1. Screening of 84 plants against enterobacteria. Journal of Ethnopharmacology 30(1):55-73. Camporese A, Balick MJ, Arvigo R, Esposito RG, Morsellino N, De Simone F, Tubaro A. 2003. Screening of antibacterial activity of medicinal plants from Belize (Central America). Journal of Ethnopharmacology 87(1):103-7. Carballo A. 1995A. as cited in Germosén-Robineau (2005). Plantas medicinales del Escambray Cubano. Informe TRAMIL. Laboratorio provincial de producción de medicamentos, Sancti Spiritus, Cuba. TRAMIL VII, Isla San Andrés, Colombia, UAG/U.Antioquia/enda-caribe. Carballo A. 1995B. as cited in Germosén-Robineau (2005). Cálculo de concentración y dosis de las drogas vegetales TRAMIL: Mensuraciones farmacognósticas y aproximaciones técnico-clínicas. Laboratorio provincial de producción de medicamentos, Sancti Spiritus, Cuba. TRAMIL VII, Isla San Andrés, Colombia, UAG/U. Antioquia/enda-caribe. Duke JA, Beckstrom-Sternberg SM. 1998. Dr. Duke’s Phytochemical Database, USDA – ARS – NGRL (eds.), Beltsville Agricultural Research Center, Beltsville, Maryland. http://www.ars-grin.gov/duke/ (accessed July 20, 2007). Felipe AM, Rincao VP, Benati FJ, Linhares RE, Galina KH, de Toledo CE, Lopes GC, de Mello JC, Nozawa C. 2006. Antiviral effect of Guazuma ulmifolia and Stryphnodendron adstringens on Poliovirus and Bovine Herpesvirus. Biol Pharm Bull 29(6):1092-5. Germosén-Robineau L, ed. 2005. Farmacopea vegetal caribeña, segunda edición. Santo Domingo, República Dominicana: enda-caribe, 487 pp. Herrera J. 1990. as cited in Germosén-Robineau (2005). Determinación de parámetros farmacológicos en vegetales utilizados en medicina tradicional en la Cuenca del Caribe. Informe TRAMIL. Laboratorio de fitofarmacología, Departamento de Farmacología, Facultad de Salud, Universidad del Valle, Cali, Colombia. TRAMIL V, Livingston, Guatemala, CONAPLAMED/enda-caribe. Hoehne FC. 1939. as cited in Germosén-Robineau (2005). Plantas e substâncias vegetais tóxicas e medicinais. São Paulo, Brazil: Dept. Bot. do Estado Sao-Paulo. Ed Graphicas. Hör M, Rimpler H, Heinrich M. 1995. Inhibition of intestinal chloride secretion by proanthocyanidins from Guazuma ulmifolia. Planta Medica 61(3):208-12. Navarro MC, Montilla MP, Cabo MM, Galisteo M, Caceres A, Morales C, Berger I. 2003. Antibacterial, antiprotozoal and antioxidant activity of five plants used in Izabal for infectious diseases. Phytotherapy Research 17(4):325-9. Yukes JE, Balick MJ, Kronenberg F, Reiff M, Johnson K. 2002-2003. Urban Ethnobotany Project, Phase III - Dominican herbal remedies for women's health. Unpublished field notes. Manuscript on file, The New York Botanical Garden, Bronx, NY. 261
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DOMINICAN MEDICINAL PLANTS: A GUIDE
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Este libro está dedicado a la comu
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Gilda Pérez. We thank the Rosentha
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PART 1 INTRODUCTION AND HOW TO USE
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York Poison Control Center. Support
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controlled clinical trials is given
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Heading DOMINICAN MEDICINAL USES Pl
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comparing these specimens with herb
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PART 2: QUICK GUIDE TO HOME REMEDIE
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Warfarin: fruit may inhibit anticoa
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Clinical Data No human clinical tri
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analgesic, anti-inflammatory, antim
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Safety The fruit is generally consi
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for allergic reaction in gluten-sen
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Fruit. Dominican Medicinal Uses The
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oxide formation, serine proteinase
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Caffeine has been investigated in h
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Entire plant shown to be hepatotoxi
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Warfarin (risk of bleeding). Clinic
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Flecha An aromatic, alcohol-based l
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Plant Part Used Leaf. Dominican Med
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disease, hypertension, menopausal h
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Leaf: decoction, orally, for pain,
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oil, topically, for sinus infection
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* See entry for Roble in “Part 3:
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Aqueous root extract given at moder
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See Hierba mora. Zanahoria* Carrot
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Aguacate OTHER COMMON NAMES Hojas d
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infections and cough (based on sign
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Activity/Effect Preparation Design
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Craigmill AL, Seawright AA, Mattila
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Availability: As a popular culinary
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Clinical Data: Capsicum spp. Activi
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Cruz L, Castaneda-Hernandez G, Nava
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- Upper or lower respiratory tract
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Roberge RJ, Leckey R, Spence R, Kre
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estrogenic effect in the human body
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Laboratory and Preclinical Data: Se
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Effect Not Demonstrated Activity/Ef
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Yukes JE, Balick MJ, Kronenberg F,
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Laboratory and Preclinical Data: Oc
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Duke JA, Beckstrom-Sternberg SM. 19
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For treating sinusitis and headache
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Laboratory and Preclinical Data: Ci
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Traditional Preparation: The leaves
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Poso H, Wichmann K, Janne J, Luukka
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scavenging and wound healing (see
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REFERENCES Aires V, Adote S, Hicham
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mixtures and decocted or tinctured
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Laboratory and Preclinical Data: Am
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Mirone C, Albert F, Tosi A, Mocchet
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Drug Interactions: The effects of s
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Activity/Effect Preparation Study d
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Lewith GT, Godfrey AD, Prescott P.
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Contraindications: Internal use is
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Lores RI, Pujol MC. 1990. as cited
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Adverse effects in infants have bee
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Activity Preparation Study design R
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Sahraei H, Ghoshooni H, Hossein Sal
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Distinguishing Characteristics of C
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- Stomach disorders Plant Part Used
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In ethnobotanical studies conducted
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Clinical Data: Chenopodium ambrosio
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Kishore NJ, Chansouria JP, Dubey NK
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Apio (Apium graveolens) is a bienni
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For the species Cucurbita pepo: Cal
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that more investigation is needed t
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Germosén-Robineau L, ed. 1995. Hac
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Fruits are 7-12 mm long, narrowly o
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Hallfrisch J, Scholfield DJ, Behall
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avoid bruising and exposure to mois
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- Limpiar la sangre - Menopausal ho
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Hiller K. 1987. as cited in Germos
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SAFETY & PRECAUTIONS As a widely co
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- Bronchitis - Common cold - Cough
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Goda Y, Hoshino K, Akiyama H, Ishik
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25 g of butter) administered orally
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Germosén-Robineau L, ed. 2005. Far
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Availability: In New York City, the
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Liogier AH. 1985. La Flora de la Es
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enzoic acid, p-hydroxycinnamic acid
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Supratman U, Fujita T, Akiyama K, H
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orally; this recommendation is base
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Perez C, Anesini C. 1994. as cited
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Contraindications: Unknown; insuffi
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Gleason H and Cronquist A. 1991. Ma
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Traditional Uses: Café seeds are t
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Laboratory and Preclinical Data: Co
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SCIENTIFIC LITERATURE In laboratory
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Cañafístula OTHER COMMON NAMES Go
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Page 209 and 210: Yukes JE, Balick MJ, Kronenberg F,
Page 211 and 212: Clinical Data: Cinnamomum verum Act
Page 213 and 214: In ethnobotanical studies conducted
Page 215 and 216: Antinociceptive & antiinflammatory
Page 217 and 218: Signs of intoxication from ingestin
Page 219 and 220: Yukes JE, Balick MJ, Kronenberg F,
Page 221 and 222: Activity/Effect Preparation Design
Page 223 and 224: Coriander (English). SCIENTIFIC NAM
Page 225 and 226: Blumenthal M, Busse WR, Goldberg A,
Page 227 and 228: the following nutrients: calcium, c
Page 229 and 230: Traditional Preparation: To prepare
Page 235 and 236: Gruenwald J, Brendler T, Jaenicke C
Page 237 and 238: Clinical Data: Vaccinium macrocarpo
Page 241 and 242: Grant P. 2004. Warfarin and cranber
Page 243 and 244: The wood of is also good for cleans
Page 245 and 246: REFERENCES Balick MJ, Kronenberg F,
Page 247 and 248: leaf-edges. Flowers grow singly and
Page 249 and 250: Dans AM, Villarruz MV, Jimeno CA, J
Page 251 and 252: facilities, some respondents report
Page 255 and 256: Eucalipto OTHER COMMON NAMES Eucaly
Page 257 and 258: Laboratory and Preclinical Data: Eu
Page 259: Distribution: This plant is native
Page 263 and 264: In one human clinical trial conduct
Page 267 and 268: nervios), a sedative tea is prepare
Page 271 and 272: Rolland et al. 1988. as cited in Ge
Page 275 and 276: - Vaginal infections Plant Part Use
Page 277 and 278: and can be taken as a remedy for la
Page 279 and 280: - Skin disorders - Upper or lower r
Page 281 and 282: Hierba Mora OTHER COMMON NAMES Yerb
Page 283 and 284: Clinical Data: Solanum americanum A
Page 285 and 286: Sultana S, Perwaiz S, Iqbal M, Atha
Page 287 and 288: calcium channel blockers and antihy
Page 291 and 292: Hawthorn M, Ferrante J, Lchowski E,
Page 293 and 294: Plant Part Used: Seeds and the oil
Page 295 and 296: Okwuasaba FK, Osunkwo UA, Ekwenchi
Page 299 and 300: Traditional Uses: Hinojo is associa
Page 301 and 302: Blumenthal M, Busse WR, Goldberg A,
Page 303 and 304: BOTANICAL DESCRIPTION Jagua (Genipa
Page 305 and 306: - Childbirth - labor pain - Fever -
Page 307 and 308: Clinical Data: Zingiber officinale
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Bhandari U, Shamsher AA, Pillai KK,
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Kar A, Choudhary BK, Bandyopadhyay
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Sugaya A, Tsuda T, Sugaya E, Usami
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along the sides of branches with wh
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the unripe fruit administered intra
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U.S. Department of Agriculture, Agr
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present in the citrus fruit rind. S
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Murcia MA, Jiménez AM, Martínez-T
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greater than the estimated correspo
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Duke JA, Beckstrom-Sternberg SM. 19
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Plant Part Used: Leaves. Traditiona
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SCIENTIFIC NAME Agave spp.; most co
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- Abortifacient - Contraception - I
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Balick MJ, Kronenberg F, Ososki AL,
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± 1.46 g/kg when administered intr
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Traditional Uses: Manzana is consid
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Laboratory and Preclinical Data: Ch
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BOTANICAL DESCRIPTION Naranja agria
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REFERENCES Allison DB, Cutter G, Po
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or blockage of the digestive tract,
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Orégano Poleo OTHER COMMON NAMES O
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- Inflammation - Limpiar el sistema
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SCIENTIFIC LITERATURE Medline liter
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and as a source of sugar whereas th
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Boettger-Tong H, Shipley G, Hsu CJ,
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Distribution: Originally native to
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Dominican Republic, a decoction of
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- Uterine fibroids - Wounds Plant P
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Laboratory and Preclinical Data: Al
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Lee KH, Kim JH, Lim DS, Kim CH. 200
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active compounds include pyridine a
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- Nightsweats - Prostate disorders
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DOMINICAN MEDICINAL USES In ethnobo
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Yildirim A, Mavi A, Oktay M, Kara A
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Effect Not Demonstrated Activity/Ef
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to tomillo have been reported; howe
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Mikus J, Harkenthal M, Steverding D
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SAFETY & PRECAUTIONS The fruit and
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Laboratory and Preclinical Data: Ci
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Grenier J, Fradette C, Morelli G, M
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- Leukemia - Menstrual disorders -
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Clinical Data: Uncaria tomentosa Ac
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Carvalho MV, Penido C, Siani AC, Va
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Sandoval-Chacon M, Thompson JH, Zha
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SAFETY & PRECAUTIONS TRAMIL describ
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- Liver disorders - Menopausal hot
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Kumarasamy Y, Cox PJ, Jaspars M, Na
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mL milliliter(s) mm millimeter(s) m
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Divided: Cut into distinct parts, a
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such as ferns and cycads Stamen: Th
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Dominican Medicinal Plants: A Guide for Health Care Providers

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