Dominican Medicinal Plants: A Guide for Health Care Providers

Activity/Effect Preparation Design & Model Results Reference
Uterine stimulant Aqueous
decoction
(steeped for 10
min) of fruit
and leaf
In vitro using the
isolated uterus of
mice (from animals
in estrus)
Significant stimulation of
uterine muscle exhibited at
a dosage of 16.66 mg
plant/mL H 2 O
Herrera 1986
Vasorelaxant
Leaf extract
(aqueous)
In vitro: isolated rat
aorta
Active; showed significant
vasorelaxant effect
Owolabi et al. 2005
REFERENCES
Abe F, Nagafuji S, Okawa M, Kinjo J, Akahane H, Ogura T, Martinez-Alfaro MA, Reyes-Chilpa R. 2005.
Trypanocidal constituents in plants 5. Evaluation of some Mexican plants for their trypanocidal activity and
active constituents in the seeds of Persea americana. Biological & Pharmaceutical Bulletin 28(7):1314-
1317.
Adeyemi OO, Okpo SO, Ogunti OO. 2002. Analgesic and anti-inflammatory effects of the aqueous extract of leaves
of Persea americana Mill (Lauraceae). Fitoterapia 73(5):375-380.
Alvizouri-Munoz M, Carranza-Madrigal J, Herrera-Abarca JE, Chavez-Carbaial F, Amezcua-Gastelum JL. 1992.
Effects of avocado as a source of monounsaturated fatty acids on plasma lipid levels. Arch Med Res
23(4):163-7.
Appelboom T, Schuermans J, Verbruggen G, Henrotin Y, Reginster JY. 2001. Symptoms modifying effect of
avocado/soybean unsaponifiables (ASU) in knee osteoarthritis. A double blind, prospective, placebocontrolled
study. Scand J Rheumatol 30(4):242-7.
Blanco C, Carrillo T, Castillo R, Quiralte J, Cuevas M. 1994. Avocado hypersensitivity. Allergy 49(6):454-9.
Blotman F, Maheu E, Wulwik A, Caspard H, Lopez A. 1997. Efficacy and safety of avocado/soybean
unsaponifiables in the treatment of symptomatic osteoarthritis of the knee and hip. A prospective,
multicenter, three-month, randomized, double-blind, placebo-controlled trail. Rev Rhum Engl Ed
64(12):825-34.
Carballo A. 1995. as cited in Germosén-Robineau (1997). Cálculo de concentración y dosis de las drogas vegetales
TRAMIL: mensuraciones farmacognósticas y aproximaciones técnico-clínicas. TRAMIL VII. Isla San
Andrés, Colombia, enda-caribe/UAG/U. Antioquía, 19 pp.
Carranza-Madrigal J, Herrera-Abarca JE, Alvizouri-Munoz M, Alvarado-Jimenez MR, Chavez-Carbajal F. 1997.
Effects of a vegetarian diet vs. a vegetarian diet enriched with avocado in hypercholesterolemic patients.
Arch Med Res 28(4):537-41.
Carranza J, Alvizouri M, Alvarado MR, Chavez F, Gomez M, Herrera JE. 1995. [Effects of avocado on the level of
blood lipids in patients with phenotype II and IV dyslipidemias.] Arch Inst Cardiol Mex 65(4):342-8.
Castro O, Gutierrez JM, Barrios M, Castro I, Romero M, Umana E. 1999. [Neutralization of the hemorrhagic effect
induced by Bothrops asper (Serpentes: Viperidae) venom with tropical plant extracts]. [Spanish] Revista de
Biologia Tropical 47(3):605-616.
Colquhoun DM, Moores D, Somerset SM, Humphries JA. 1992. Comparison of the effects on lipoproteins and
apolipoproteins of a diet high in monounsaturated fatty acids, enriched with avocado and a highcarbohydrate
diet. Am J Clin Nutr 56(4):671-7.
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