Dominican Medicinal Plants: A Guide for Health Care Providers

Activity/Effect Preparation Design & Model Results Reference
Hypoglycemic Hydroalcoholic
(1:1) extract of
the dried aerial
parts;
administered by
gastric
intubation; dose:
45.0 mg/kg
In vivo: rats Active Aswal et al.
1984
Hypoglycemic
Hypoglycemic &
hypolipidemic
Hypotensive
Hypotensive
Immunoglobulin
production
inhibition
Immunostimulant
Interleukin-1-beta
release inhibition,
cyclooxygenase 2
inhibition &
cytokinin antagonist
Rhizome,
ethanolic extract
(80%); dose:
100.0 mg/kg,
administered
intragastrically
Dried rhizome,
administered as
part of feed
(0.5%)
Dried rhizome
aqueousmethanolic
extract (1:1)
administered
intravenously
Dried rhizome
aqueous low
speed
supernatant;
doses of 10, 25,
50, 100 & 200
mg (dry weight
of plant)/kg,
intravenously
Rhizome, saline
extract;
concentration:
10.0 mg/mL
Ethanolic extract
(5%) of the dried
fibers; dose:
25.0 mg/kg
administered
intragastrically
Dried rhizome
extract
In vivo: rabbits Active Mascolo et al.
1989
In vivo: male albino
rats
In vivo: rats
In vivo: dogs
In vitro: rat
lymphocytes
Active based on evaluation
of serum glucose levels &
lipid profile
Active; dose of 0.25 m/kg
showed hypotensive
activity & dose of 0.5 g/kg
showed significant activity
(P < 0.01)
Showed highly dosedependent
& significant
activity with a maximum
effective dose of 100
mg/kg; pulse pressure
decreased; presence of
potassium ions in the
extract did not produce
significant change
Ahmed &
Sharma 1997
Kasahara et al.
1983
Hantrakul &
Tejason 1976
Active Kaku et al. 1997
In vivo: mouse Active Puri et al. 2000
In vitro: cell culture
of THP-1 monocytes
with beta-amyloid
peptide-induced
chemokine &
cytokine expression
Active; inhibited
chemokine & cytokine
expression
Grzanna et al.
2004
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