Dominican Medicinal Plants: A Guide for Health Care Providers

Activity/Effect Preparation Design & Model Results Reference
Hormone
Keenan et al. 1998
modulation
Hypocholesterolemic
& antioxidant
REFERENCES
Root, acute feeding;
vs. retinoic acid (a
metabolite of
carrot)
Root; dietary
In vitro: isolated
rabbit ovarian
perfusion system
In vivo: rats;
duration: 3 wks
Carrot significantly
decreased progesterone
secretion & human
chorionic
gonadotropin-induced P
secretion; retinoic acid
stimulated progesterone
secretion
Active; lowered liver
cholesterol levels;
increased fecal steroid
excretion; improved
antioxidant status;
suggest potential
cardiovascular
protective effects
Nicolle et al. 2003
Abbey M, Noakes, M, Nestel PJ. 1995. Dietary supplementation with orange and carrot juice in cigarette smokers
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Bailey Hortorium Staff. 1976. Hortus Third: A Concise Dictionary of Plants Cultivated in the United States and
Canada. New York: Macmillan Publishing Company, 1290 pp.
Balasubramaniam P, Pari L, Menon VP. 1998. Protective effect of carrot (Daucus carota L.) against lindaneinduced
hepatotoxicity in rats. Phytotherapy Research 12(6):434-436.
Balick MJ, Kronenberg F, Ososki AL, Reiff M, Fugh-Berman A, O’Connor B, Roble M, Lohr P, Atha D. 2000.
Medicinal Plants used by Latino healers for women’s health conditions in New York City. Economic
Botany 54: 344-57.
Bishayee A, Sarker A, Chatterjee M. 1995. Hepatoprotective activity of carrot (Daucus carota L.) against carbon
tetrachloride intoxication in mouse liver. Journal of Ethnopharmacology 47(2):69-74.
Duke J. 1992. Handbook of biologically active phytochemicals and their activities. Boca Ratón: CRS Press.
Gambhir SS, Sen SP, Sanyal AK, Das PK. 1979. Antispasmodic activity of the tertiary base of Daucus carota, Linn.
seeds. Indian Journal of Physiology & Pharmacology 23(3):225-228.
Guedon C, Ducrotte P, Antoine JM, Denis P, Colin R, Lerebours E. 1996. Does chronic supplementation of the diet
with dietary fiber extracted from pea or carrot affect colonic motility in man? British Journal of Nutrition
76(1):51-61.
Hedren E, Diaz V, Svanberg U. 2002. Estimation of carotenoid accessibility from carrots determined by an in vitro
digestion method. European Journal of Clinical Nutrition 56(5):425-430.
Keenan DL, Dharmarajan AM, Zacur HA. 1998. Dietary carrot results in diminished ovarian progesterone secretion,
whereas a metabolite, retinoic acid, stimulates progesterone secretion in the in vitro perfused rabbit ovary.
Fertil Steril 69(4):789-790.
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