scientific program • symposia - American Society for Reproductive ...

SCIENTIFIC PROGRAM • SYMPOSIA
Wednesday, October 19, 2011 5:15 pm – 5:45 pm
Society for Male Reproduction and Urology Mini-Symposium
2010 WHO SPERM REFERENCE VALUES - CLINICAL
SIGNIFICANCE OF COUNT, MOTILITY AND MORPHOLOGY
Edmund S. Sabanegh, Jr., M.D.
Cleveland Clinic
Needs Assessment and Description
Semen analysis is one of the most basic, yet important,
tests for assessing the reproductive function in men and
often is utilized during the course of evaluating men for
subfertility/infertility. Over the past 30 years, the World Health
Organization (WHO) Manual for the Examination of Human
Semen has been recognized as providing global standards
for semen analysis and has been used extensively by
research and clinical laboratories throughout the world. The
2010, 5th edition, provides revisions, additional explanations
and supporting evidence for methods of analysis. Based
on data of the semen quality of fertile men, whose partners
had a time to pregnancy of 12 months or less, the manual
gives the 5th centile as the lower reference limit along
with the complete distribution for each semen parameter.
This session, designed for physicians and allied healthcare
professionals with an interest in male fertility, will provide an
update of the 2010 WHO Reference Values, focusing on the
clinical significance of count, motility, and morphology.
Room 330 D
81
Learning Objectives
At the conclusion of this interactive session, participants
should be able to:
1. Identify the major changes in the 2010 WHO Manual for
the Examination of Human Semen.
2. Describe the clinical significance of sperm count, motility
and morphology and the implications for infertility.
ACGME COMPETENCY
Medical Knowledge
Patient Care
TEST QUESTION:
In the 2010 (5th) edition of the WHO Manual for the
Examination of Human Semen, the lower threshold limits for
sperm concentration/motility/morphology are:
A. 20 million/mL; 40% total motile/15%
B. 20 million/mL; 50% progressive; 15%
C. 15 million/mL; 40% total motile; 15%
D. 15 million/mL; 32% progressive; 4%