scientific program • symposia - American Society for Reproductive ...

SCIENTIFIC PROGRAM • INTERACTIVE SESSIONS
Monday, October 17, 2011 1:15 pm – 2:15 pm
Interactive Session
ANTICHLAMYDIAL ANTIBODY SCREENING OF THE INFERTILITY
PATIENT
Presented by the Reproductive Immunology Special Interest Group
Danny J. Schust, M.D. (Chair)
University of Missouri School of Medicine
Guangming Zhong, M.D., Ph.D.
University of Texas Health Science Center
Jared C. Robins, M.D.
The Warren Alpert Medical School of Brown University
Needs Assessment and Description
Chlamydia trachomatis is the most prevalent bacterial
sexually transmitted infection, and 20% of women with C.
trachomatis get pelvic inflammatory disease (PID). The risk
for tubal infertility doubles with each subsequent episode
of PID. Women infected with C. trachomatis who remain
asymptomatic may still suffer the fertility consequences of
infection.
The gold standards used to test for tubal factor infertility
continue to be laparoscopy or hysterosalpingography
(HSG). Interest in C. trachomatis antibody testing has been
reinvigorated by improved testing specificity and sensitivity,
and the push by patients, providers and reimbursement
sources for inexpensive and noninvasive testing and
treatments for fertility patients.
During this interactive session, advances in C. trachomatis
antibody testing and its relevance to male and female
fertility will be reviewed. The utility of a variety of
available and upcoming tests and compare their value
to laparoscopy and/or hysterosalpingography will be
discussed.
Room 224 C/D
85
Learning Objectives
At the conclusion of this session, participants should be able
to:
1. List the advantages and disadvantages of antichlamydial
antibody testing for male and female patients with
impaired fertility.
2. Discuss the role of heat shock protein cross reactivity in
chlamydia-related infertility and pregnancy wastage.
ACGME COMPETENCY
Medical Knowledge
Patient Care
Monday, October 17, 2011 1:15 pm – 2:15 pm
Interactive Session
EMBRYO SELECTION: GENOMICS, METABOLOMICS AND
MORPHOLOGICAL ASSESSMENT
Presented by the Latin American Association for Reproductive Medicine
(ALMER)
Carlos E. Sueldo, M.D. (Chair)
University of California San Francisco
Mandy Katz-Jaffe, Ph.D.
Colorado Center for Reproductive Medicine
Denny Sakkas, Ph.D.
Yale University School of Medicine
Needs Assessment and Description
Traditionally, embryo selection prior to embryo transfer was
based on morphological assessment. More recently, the role
of genomics and metabolomics were introduced as very
effective alternatives to better select high quality embryos
for transfer. There is a need to identify the place of these
newer techniques in ART, and also how they compare to the
more traditional embryo selection process.
Learning Objectives
At the conclusion of this interactive session, participants
should be able to:
1. Outline the present status of genomics and metabolomics
in ART.
2. Summarize the advantages and disadvantages of
morphological embryo selection vs. the newer
techniques.
Room F 5
TEST QUESTION:
After participating in this session, I will do the following in my
practice:
A. Perform only diagnostic laparoscopy and tubal lavage to
evaluate fallopian tubal patency in new fertility patients.
B. Perform only hystersalpingography (HSG) to establish
fallopian tubal patency in new fertility patients.
C. Consider anti-chlamydial antibody testing prior to more
invasive testing for fallopian tubal patency in new fertility
patients.
D. Perform only saline infusion sonohysterography (SIS) to
evaluate fallopian tubal patency in new fertility patients.
E. Not investigate fallopian tubal patency in new fertility
patients.
F. Not applicable to my area of practice.
ACGME COMPETENCY
Medical Knowledge
TEST QUESTION:
A 35-year-old infertile female has had 3 consecutive
miscarriages, all with documented abnormal karyotype. In a
current IVF cycle, she has 5 expanded blastocysts, all displaying
similar morphology. After participating in this session, to optimize
her chances of avoiding a subsequent miscarriage, in my
practice I will use the following diagnostic technique for embryo
selection for transfer:
A. Metabolomics
B. Proteomics
C. 23- pair chromosome aneuploidy screening
D. Glucose testing
E. Gene defect screening
F. Not applicable to my area of practice.