ANNUAL REPORT - Department of Biotechnology

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JK Agri Genetics, Hyderabad cry1Ac M/s Kaveri Seeds Co. P. Ltd, S'bad cryX Krishidhan Seeds, Jalna cry1Ac, cryX Mahyco, Mumbai cryX Metahelix Life Sciences, Bangalore cry1C Namdhari Seeds Pvt. Ltd, Bangalore cryX Nandi Seeds Pvt. Ltd Mehbubnagar cry1Ac Nath Seeds, Aurangabad GFM cry1A M/s. Navkar Hybrid Seeds Ltd., Ahmedabad GFM cry1A Nuziveedu Seeds, Hyderabad cry1Ac, cryX Prabhat Agri Biotech Ltd. Hyderabad cry1Ac, cryX Pravardhan Seeds Pvt. Ltd Hyderabad cryX Proagro Seeds Co. Ltd Hyderabad cry1Ac, cryX Rasi Seeds Ltd., Attur cryX Safal Seeds & Biotech Ltd., Aurangabad GFM cry1A Seed Works Pvt. Ltd., Hyderabad cry1Ac Solar Agro Tech Pvt. Ltd., Rajkot cryX Syngenta India Ltd., Pune Vip-3A, cry1Ab Tulsi Seeds, Guntur cry1Ac, cryX Uniphos Enterprises Ltd., Mumbai GFM cry1A Vibha Agrotech Ltd. Hyderabad cry1Ac, cryX Vikki's Agrotech, Hyderabad cryX Vikram Seeds Ltd, Ahmedabad cry1Ac, cryX Zuari Seeds Ltd. Bangalore GFM cry1A 7. Groundnut ICRISAT, Hyderabad chitinase gene from Rice (Rchit) 8. Mustard UDSC, New Delhi barnase & barstar 9. Okra Mahyco, Mumbai cry1Ac,cry2Ab 10. Potato CPRI, Shimla RB gene derived from Solanum bulbocastanum 11. Rice IARI, New Delhi cry1Aa - cry1B Mahyco, Mumbai cry1Ac, cry2Ab TNAU, Tamil Nadu rice chitinase (chi11) or tobacco osmotin gene 12. Tomato IARI, New Delhi antisense replicase gene of tomoto leaf curl virus Mahyco, Mumbai cry2Ab The workshops, seminars and symposia organized by the Department of Biotechnology on biosafety rules and regulations have increased the awareness among the research institutions working in the area of r- DNA technology. At present there are 358 IBSCs constituted at various public-funded institutions, universities, private R&D institutions and industries. 155 Bioprocess and Product Development
MEC met five times during the year to review the field trial data generated in multi-location field trials on Bt cotton. MEC also evaluated the data generated on Bt. brinjal, Bt. cabbage and Bt. cauliflower in multilocation field trials. The MEC recommended for conduct of large scale field trials and also for commercial release of Bt. cotton hybrids expressing cry1Ac gene (MON-531 event), cry1Ac (JK event No. 1), cry1Ac & cry2Ab genes (MON 15985 event) and GFM cry1A gene. The department played an important role in release of 38 new Bt. cotton hybrids suitable for commercial cultivation in north, central 156 and south zones by GEAC. Thirteen Central Monitoring Teams were constituted by the Department to monitor multi-location field trials of Bt. cotton, Bt. brinjal, Bt. cauliflower & Bt. cabbage In r-DNA pharmaceuticals area, most of the applications filed for approvals from RCGM were by private institutions. Table-2 provides information on the products, approved by RCGM for conduct of preclinical toxicity studies and recommendations to conduct human clinical trials during the year. List of r-DNA Pharmaceuticals approved for pre-clinical and clinical studies during 2006. Sl. No. Product Institute/Industry 1. rh-PEG-Interferon alpha 2b M/s. Cadila Healthcare Ltd., Ahmedabad 2. rh-polysialated Interferon alpha 2b M/s. Serum Institute of India Ltd, Pune 3. Modified rh-tPA-reteplase M/s. Biocon India Ltd., Bangalore 4. r-reteplase M/s. Shantha Biotechnics Pvt. Ltd., Hyderabad 5. rh-polysialated erythropoietin M/s. Serum Institute of India Ltd, Pune 6. Pegylated rh-erythropoietin M/s. Serum Institute of India Ltd, Pune 7. rh-Erythropoietin Alpha M/s. INTAS Biopharmaceuticals Ltd., Ahmedabad 8. rh-Interferon beta 1b M/s. Cadila Healthcare Ltd., Ahmedabad 9. Tetravalent vaccine (DPT+r-HB) M/s. Indian Immunologicals, Hyderabad 10. r-monoclonal tetanus immunoglobulin M/s. Bharat Serum and Vaccines Ltd, Mumbai 11. Recombinant Darbepoietin M/s Dr Reddy's Laboratories, Hyderabad 12. Recombinant PvRII ICGEB, New Delhi DBT Annual Report 2006-07 Table-2
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ANNUAL REPORT 2006 - 2007 Departmen
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CONTENTS Chapter-1: An Overview 1 A
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Chapter-6: Biotechnology for Societ
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An Overview Biotechnology is a set
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In a project to identify, map and t
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Medicinal and Aromatic Plants Four
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wax related gene fragments having h
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esearch; appropriate regulatory mec
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Science or Food Science & Technolog
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and the National Research Centre Ca
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many sophisticated instrumentation
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Advisory Structure Standing Advisor
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Human Resource Development The Depa
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a rapidly advancing area and teache
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per year for a period of three year
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this fellowship and 9 students have
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80 70 60 50 40 30 20 10 0 1600 1400
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throughput molecular marker service
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plasmamembrane localisation of GFP-
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antibiotic biosynthesis in Streptom
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the reporting period. Out of these,
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in progress. Besides multiplication
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primers (Operon) under the series O
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a total of 326 cotyledonary node ex
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Magnaportha grisea, showed signific
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some diseases are the two most impo
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For utilization of Multiple Aleuron
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BGA transformations, MPS transforma
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development of root knot nematode,
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plant growth and development. Due t
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significant weed control at seedlin
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three rice accessions with enhanced
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oth adults and nymphs. First year m
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c-DNA probes were developed using a
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across all the 462 clones with allo
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R & D programme have also been supp
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Inauguration of Butterfly Park by S
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Germlasing of NAPs conversed in gen
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patchouli were found to be similar
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With a view to isolate the taxol bi
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attributed to the ribosome inactiva
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(RBSS) assay. Study was supported a
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showed sign of spoilage even after
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ody hepatitis (IBH) in domestic fow
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FSH, IGF-1 and cumulus granulosa mo
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uffalo UTMP cDNA exhibited 94.5, 88
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Biosurfactant Work on screening of
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conotoxins along with the posttrans
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Oligonucleotide probe for monitorin
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similarity with the already reporte
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studies on expressed sequences of t
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factors. Scientists at Sree Chitra
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A study was implemented at NCCS, Pu
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Medical Biotechnology Health relate
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Page 115 and 116: Delhi. The protocol for 4-colour wh
Page 117 and 118: Cross Sectional Morphology of the T
Page 119 and 120: Virus Research Centers or Networks
Page 121 and 122: As the clinical trials ae planned t
Page 123 and 124: een implemented for both basic and
Page 125 and 126: low cost for rapid diagnosis of dis
Page 127 and 128: Under the multi-centric project on
Page 129 and 130: The genetic basis of Type2 diabetes
Page 131 and 132: Floor model RBC Reactor - Close-up
Page 133 and 134: analyzed for the selection of best
Page 135 and 136: yield of hydrogen in the first stag
Page 137 and 138: Operational guidelines for collecti
Page 140 and 141: Programmes for SC and ST Population
Page 142 and 143: section in the Western Dun Valley t
Page 144 and 145: aromatic grasses. These women are g
Page 146 and 147: Poultry and Livestock Farming In an
Page 148: conducted on mushroom cultivation,
Page 151 and 152: probiotic selected strains of Lacto
Page 153 and 154: hydratase activity was shown by eig
Page 155 and 156: At Birla Institute for Scientific R
Page 157 and 158: study at Osmania University and IIC
Page 159 and 160: DBT Annual Report 2006-07 152
Page 161: In the area of recombinant pharma s
Page 166 and 167: Biotechnology Information System Ne
Page 168 and 169: Bioinformatics National Certificati
Page 170 and 171: Meetings 1) International Conferenc
Page 172 and 173: Biotechnology Parks and Incubators
Page 174 and 175: International Collaboration Interna
Page 176 and 177: elow: Contraceptive and Reproductiv
Page 178 and 179: USP method. These included 59 smear
Page 180 and 181: Danforth); others (IHBT & possibly
Page 182: Memorandum of Agreement between Dep
Page 185 and 186: cytokine-mediated regulation of int
Page 187 and 188: In stem cell research, the studies
Page 189 and 190: two pathogens in the acidic environ
Page 191 and 192: software developed by TCS with supp
Page 193 and 194: eleased from activated microglia ar
Page 195 and 196: Genetic linkage mapping in Catharan
Page 197 and 198: three of the BACs (374Kb) of chromo
Page 199 and 200: ATPase mRNA binding protein, cathep
Page 202: Public Sector Undertaking Bharat Im
Page 205 and 206: complete protection against a paras
Page 208 and 209: Administration and Finance Administ
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GENDER BUDGETING CELL The Departmen
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6. Prof. K. Dharmalingam Member Hea
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19. Prof. Mahtab S. Bamji Member Em
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INTER-DISCIPLINARY RESEARCH COMMITT
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MONITORING-CUM-EVALUATION COMMITTEE
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Dr. Debi P. Sarkar, Professor & Hea
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TASK FORCE ON BIOTECHNOLOGY BASED P
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TASK FORCE ON AGRICULTURAL BIOTECHN
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Prof. H. Sharat Chandra, Director,
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NATIONAL BIORESOURCE DEVELOPMENT BO
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Scientist 'F' Forest Research Insti
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Prof. B. N. Johri Department of Bio
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Annexure-III DBT SPONSORED UNIVERSI
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16. University of Jammu, 10 JNU-CET
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32. Visva-Bharati, 10 JNU-CET Prof
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46. Banaras Hindu 12 JNU-CET Prof.
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LONG TERM 237 Annexure-IV BIOTECHNO
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239 Annexures
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241 Annexures
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243 Annexures
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245 Annexures
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SOFTWARE AVAILABLE WITH BTISNet CEN
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249 Annexures
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12. Jagadish N, Rana R, Mishra D, G
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42. Vats D, Vishwakarma RA, Bhattac
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15. Singh, S., Upadhyay, A.K., Ajay
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PATENTS FILED / SEALED Dr. V. P. Ka
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22. Johny S, Kanginakudru S, Murali
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11. Mallappa, C., Yadav, V., Negi,
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Annexure-X STATEMENT OF BUDGET ESTI
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GST H2O2 HAU HCH hck HCMI HDAC1 HIC
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SATB1 SDL SFC SGOT SGPGI SGPT SH Si
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ANNUAL REPORT - Department of Biotechnology

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