11. Mallappa, C., Yadav, V., Negi, P., and Chattopadhyay, S. (2006) A bzip transcription factor, GBF1, regulates blue light mediated photomorphogenic growth in Arabidopsis. Journal Biological Chemistry 281, 22190-22199 12. Dutta A, Singh D, Kumar S, Sen J (2007) Transcript pr<strong>of</strong>iling <strong>of</strong> terpenoid indole alkaloid pathway genes and regulators reveals strong expression <strong>of</strong> repressors in Catharanthus roseus cell cultures. Plant Cell Reports (in press) 13. Kumar S, Dutta A, Sinha AK, Sen J (2007) Cloning, characterization and localization <strong>of</strong> a novel basic peroxidase gene from Catharanthus roseus. FEBS Journal (in press) INSTITUTE OF BIORESOURCES AND SUSTAINABLE DEVELOPMENT, IMPHAL 1. Rama Kant, Tiwari, O.N., Tandon, Richa and Tiwari, G.L. (2006): On validity <strong>of</strong> the genus Aphanothece Nageli Chroococcales, Cyanobacteria, Jour. Indian Bot. Soc. Vol.85 (1-4), 61-65 2. Tiwari, O.N., Singh, M.R.K., Dhar, Dolly Wattal, Tiwari, G.L. (2006): Cultural studies and physiological characterization <strong>of</strong> diazotrophic cyanobacterial isolates <strong>of</strong> rice fields <strong>of</strong> Manipur, India Nat. Jour. <strong>of</strong> Life Sciences, 3(2), 109-113 3. M.S. Singh and Bijaya Th.: Response <strong>of</strong> Rice (Oryza sativa) to Bi<strong>of</strong>ertilizers in combination with FYM and Nitrogen J.Ecobiol. 18(4) 363-369 (2006) ISSN: 0970-9037-06-18-363 4. Rana, V.S. and Blazquez, M.A.: Chemical composition <strong>of</strong> the essential oil <strong>of</strong> Gaultheria fragrantissima Wall. leaves. Indian Perfumer, 2006, 50-, 51-52 5. Basudha, Ch. and Singh, N.S. 2007: Biodiversity and conservation status <strong>of</strong> freshwater fishes <strong>of</strong> Manipur. In: Biodiversity Conservation and Legal Aspects. (Eds. A.K. Kandya & Asha Gupta) Aaviskar Publishers & Distributors, Jaipur, 72-89 INSTITUTE OF LIFE SCIENCES, BHUBANESHWAR 1. Kar P, Supakar PC, Expression <strong>of</strong> Stat5A in tobacco chewing-mediated oral squamous cell carcinoma. Cancer Letter, 2006, 240: 306-311. (IF: 2.938) 2. Debata PR. Panda H and Supakar PC. Altered expression <strong>of</strong> trefoil factor 3 and cathepsin L. gene in rat kidney during aging. Biogerontology, 2006, in press. (IF: 3.11) 3. Sekhar PN, Kavi Kishor PB, Reddy LA, Mondal P, Dash AK, Kar M, Mohanty S, Sabat SC. In silico modling and hydrogen peroxide binding study <strong>of</strong> rice catalase. In Salico Biology 2006, 6, 0041. (IF: 3.45) 4. Parveen S, Sahoo SK. Nanomedicine: Clinical applications <strong>of</strong> Polyethylene Glycol Conjugated Proteins and Drugs. Clinical Pharmacokinetics, 2006, 45(10): 965-88. (IF: 5.453) 5. Satapathy AK, Sartono E, Sahoo PK , Dentener MA, Machael E, Yazdanbakhsh M, Ravindran B. Human bancr<strong>of</strong>tian filariasis: Immunological markers <strong>of</strong> morbidity and infections. Microbes Infection 2006, 9-10: 2414-2423. (IF: 3.573) 261 Annexures
6. Mantri CK, Mohapatra SS, Ramamurthy T, Ghosh R, Colwell RR, Singh DV. Septaplex PCR Assay for Rapid Identification <strong>of</strong> Vibrio cholerae including Detection <strong>of</strong> Virulence and intSXT genes. FEMS Microbiology Letters. 2006, in press. (IF:2.057) 7. Mohapatra SS, Ramachandran D, Mantri CK, Singh DV. Characterization <strong>of</strong> a new ribotype <strong>of</strong> Vibrio cholerae O1 biotype E1 Tor serotype Inaba strains isolated in Trivandrum, Southern India. Journal <strong>of</strong> Medical Microbiology. 2006. (IF: 2.484) 8. Mohanty A, Kar P, Mishra K, Singh DV, Mohapatra N, Kar S, Dash AP, Hazra RK. Multiplex PCR assay for the detection <strong>of</strong> Anopheles fluviatilis species complex, human host preference, and Plasmodium falciparum sporozoite presence, using a unique mosquito processing methods. American Journal <strong>of</strong> Tropical Medicine & Hygiene 2006. (IF: 2.013) 9. Das SK, Gautam US, Chakrabartty PK, Singh A. Characterization <strong>of</strong> a symbiotically defective serine auxotroph <strong>of</strong> Mezorhizobium ciceri. FEMS Microbiology Letters 2006, 263: 244-251 (IF: 2.057) INTERNATION CENTRE FOR GENETICS ENGINEERING & BIOTECHNOLOGY, NEW DELHI The centre has published many papers in National and International peer reviewed journals during the year 2006. Some major publications are: 1. Sachdeva, S., Mohmmed, A., Dasaradhi, P.V., Crabb, B.S., Katyal, A., Malhotra, P., Chauhan, V.S. 2006. Immunogenicity and protective efficacy <strong>of</strong> Escherichia coli expressed Plasmodium falciparum merozoite surface protein-1(42) using human compatible adjuvants. Vaccine. 24(12), 2007-2016. 2. Singh, S.K., Hora, R., Belrhali, H., Chitnis, C.E., Sharma, A. 2006. Structural basis for Duffy recognition by malaria parasite Duffy-binding-like domain. Nature 439, 741-744 3. George, A.A. Sharma, M., Singh, B.N., Sahoo, N.C., and Rao, K.V.S. (2006). Transcription from a TATA and INR-less promoter: Spatial segregation <strong>of</strong> promoter function. EMBO J. 25: 811-821. 4. Choudhury, N.R., Malik, P.S., Singh, D.K., Islam, M.N., Kaliappan, K., Mukherjee, S.K. 2006. The oligomeric Rep protein <strong>of</strong> Mungbean yellow mosaic India virus (MYMIV) is a likely replicative helicase. Nucleic Acids Res. 34, 6362-6377. 5. Desai, M.K., Mishra, R.N., Verma, D., Nair, S., Sopory, S.K., Reddy, M.K. 2006. Structural and functional analysis <strong>of</strong> a salt stress inducible gene encoding voltage dependent anion channel (VDAC) from pearl millet (Pennisetum glaucum). Plant Physiol. Biochem. 44, 483-493. 6. Singla-Pareek, S.L.,Yadav, S.K., Pareek, A., Reddy, M.K., Sopory, S.K. 2006. Transgenic tobacco overexpressing glyoxalase pathway enzymes grow and set viable seeds in zinc-spiked soils. Plant Physiol. 140, 613-623. DBT Annual Report 2006-07 262
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ANNUAL REPORT 2006 - 2007 Departmen
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CONTENTS Chapter-1: An Overview 1 A
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Chapter-6: Biotechnology for Societ
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An Overview Biotechnology is a set
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In a project to identify, map and t
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Medicinal and Aromatic Plants Four
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wax related gene fragments having h
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esearch; appropriate regulatory mec
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Science or Food Science & Technolog
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and the National Research Centre Ca
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many sophisticated instrumentation
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Advisory Structure Standing Advisor
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Human Resource Development The Depa
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a rapidly advancing area and teache
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per year for a period of three year
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this fellowship and 9 students have
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80 70 60 50 40 30 20 10 0 1600 1400
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throughput molecular marker service
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plasmamembrane localisation of GFP-
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antibiotic biosynthesis in Streptom
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the reporting period. Out of these,
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in progress. Besides multiplication
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primers (Operon) under the series O
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a total of 326 cotyledonary node ex
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Magnaportha grisea, showed signific
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some diseases are the two most impo
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For utilization of Multiple Aleuron
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BGA transformations, MPS transforma
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development of root knot nematode,
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plant growth and development. Due t
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significant weed control at seedlin
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three rice accessions with enhanced
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oth adults and nymphs. First year m
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c-DNA probes were developed using a
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across all the 462 clones with allo
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R & D programme have also been supp
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Inauguration of Butterfly Park by S
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Germlasing of NAPs conversed in gen
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patchouli were found to be similar
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With a view to isolate the taxol bi
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attributed to the ribosome inactiva
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(RBSS) assay. Study was supported a
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showed sign of spoilage even after
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ody hepatitis (IBH) in domestic fow
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FSH, IGF-1 and cumulus granulosa mo
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uffalo UTMP cDNA exhibited 94.5, 88
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Biosurfactant Work on screening of
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conotoxins along with the posttrans
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Oligonucleotide probe for monitorin
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similarity with the already reporte
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studies on expressed sequences of t
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factors. Scientists at Sree Chitra
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A study was implemented at NCCS, Pu
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Medical Biotechnology Health relate
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F S C # C e lls 1000 800 600 400 20
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the pathogenesis of JE. It has been
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Delhi. The protocol for 4-colour wh
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Cross Sectional Morphology of the T
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Virus Research Centers or Networks
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As the clinical trials ae planned t
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een implemented for both basic and
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low cost for rapid diagnosis of dis
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Under the multi-centric project on
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The genetic basis of Type2 diabetes
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Floor model RBC Reactor - Close-up
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analyzed for the selection of best
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yield of hydrogen in the first stag
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Operational guidelines for collecti
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Programmes for SC and ST Population
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section in the Western Dun Valley t
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aromatic grasses. These women are g
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Poultry and Livestock Farming In an
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conducted on mushroom cultivation,
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probiotic selected strains of Lacto
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hydratase activity was shown by eig
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At Birla Institute for Scientific R
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study at Osmania University and IIC
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DBT Annual Report 2006-07 152
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In the area of recombinant pharma s
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MEC met five times during the year
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Biotechnology Information System Ne
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Bioinformatics National Certificati
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Meetings 1) International Conferenc
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Biotechnology Parks and Incubators
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International Collaboration Interna
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elow: Contraceptive and Reproductiv
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USP method. These included 59 smear
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Danforth); others (IHBT & possibly
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Memorandum of Agreement between Dep
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cytokine-mediated regulation of int
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In stem cell research, the studies
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two pathogens in the acidic environ
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software developed by TCS with supp
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eleased from activated microglia ar
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Genetic linkage mapping in Catharan
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three of the BACs (374Kb) of chromo
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ATPase mRNA binding protein, cathep
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Public Sector Undertaking Bharat Im
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complete protection against a paras
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Administration and Finance Administ
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2. As the Department wants the comm
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GENDER BUDGETING CELL The Departmen
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6. Prof. K. Dharmalingam Member Hea
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19. Prof. Mahtab S. Bamji Member Em
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- Page 228 and 229: Prof. H. Sharat Chandra, Director,
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- Page 244 and 245: LONG TERM 237 Annexure-IV BIOTECHNO
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- Page 264 and 265: PATENTS FILED / SEALED Dr. V. P. Ka
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