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ANNUAL REPORT - Department of Biotechnology

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<strong>Biotechnology</strong> Information System Network<br />

After making a mark in Information Technology, the<br />

Indian IT community is in the process <strong>of</strong> changing<br />

gears. Focus has already shifted to the industry <strong>of</strong><br />

the future - Bio-technology, also known as the<br />

science <strong>of</strong> the living organism. In this goal, we are<br />

fortunate to have a strong foundation in terms <strong>of</strong> pool<br />

<strong>of</strong> scientific talent, world class s<strong>of</strong>tware engineers<br />

and a vibrant pharmaceutical and biotech sector.<br />

Drug discovery is increasingly becoming<br />

unaffordable and risky venture. Bioinformatics holds<br />

out promise towards reducing the cost and time <strong>of</strong><br />

development <strong>of</strong> new products such as new drugs,<br />

vaccines, plants with specific properties and<br />

resistance to environmental stress, pest and<br />

diseases etc. As the full genome sequences, data<br />

from micro arrays, proteomics as well as species<br />

data at the taxonomic level become available,<br />

interrogation <strong>of</strong> these databases require<br />

sophisticated bioinformatics tools. Organizing this<br />

data into querriable and interoperable databases and<br />

developing appropriate s<strong>of</strong>tware to extract<br />

knowledge from these databases is going to be a<br />

major challenge.<br />

<strong>Biotechnology</strong> Information System(BTISnet)<br />

India was the first country in the world to establish<br />

National distributed Bioinformatics Network. Due to<br />

personal intervention and support by the then Prime<br />

Minister Late Rajiv Gandhiji, India established a<br />

Distributed Bioinformatics Network in 1986-87. The<br />

culture <strong>of</strong> use <strong>of</strong> computers in biology and<br />

importance <strong>of</strong> quantization in biology in India was the<br />

result <strong>of</strong> this network. The BTISnet covers<br />

institutions under DST, CSIR, ICMR, ICAR,<br />

Universities and Institutes under Human Resource<br />

Ministry.<br />

Today an extensive Bioinformatics Network,<br />

covering 117 institutions, spread geographically all<br />

over the country, has been established. The Network<br />

Chapter : 8<br />

is creating human resource in Bioinformatics and<br />

carrying out research in different areas <strong>of</strong><br />

Bioinformatics. Scientists <strong>of</strong> this network have<br />

published more than 1000 bioinformatics research<br />

papers in peer reviewed journals in last five years and<br />

helped in publishing more than 3000 research papers<br />

in biology/biotechnology. The network has also<br />

helped directly or indirectly several Bioinformatics<br />

companies in India. The scientists from the network<br />

have participated in major national millennium<br />

technology initiative projects <strong>of</strong> CSIR such as<br />

Biosuite <strong>of</strong> Tata Consultancy Services (TCS) or<br />

s<strong>of</strong>tware packages for visualization <strong>of</strong> bioinformatics<br />

data by Strand Genomics. The BTISnet is the first<br />

network which established BioGrid India <strong>of</strong> large<br />

bandwidth and high speed connectivity among<br />

various institutions in the country and also high<br />

performance national computing facility. Thus, this<br />

unique network has showed that India can work in<br />

network consortium mode.<br />

Major Activities during 2006-07<br />

Bioinformatics facility (BIF) for Biology Teaching<br />

through Bio Informatics (BTBI):<br />

Innovation is required not only in research but also in<br />

teaching activities <strong>of</strong> Biology and allied areas.<br />

Towards this, the department has evolved a new<br />

program, namely biology teaching though<br />

bioinformatics (BTBI) by establishing bioinformatics<br />

facilities at teaching institutions. The scheme was<br />

widely advertised in newspapers, journals, websites,<br />

E-mail list servers etc. A total <strong>of</strong> 165 applications<br />

were received out <strong>of</strong> which 52 institutions were<br />

selected and extended grants-in-aid for setting up <strong>of</strong><br />

bioinformatics facilities. The facility will be a<br />

centralized resource <strong>of</strong> an individual institution to<br />

support bioinformatics tools and resources for the<br />

enhancement <strong>of</strong> learning capabilities. A list <strong>of</strong> these<br />

52 BIF facilities is given at Annexure-V.<br />

159 <strong>Biotechnology</strong> Information System Network

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