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WNU-Summer Institute 2012 Christ Ch
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FIRST PART Epistemology: Radiation
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Radioactive substance (radioactivit
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Absorbed dose, D (gray or rad) Radi
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Activity (Bq) Fluence (cm-2 Fluence
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Natural Cosmic Cosmic rays Terrestr
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OSU, Stillwater, OK, USA, February
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Medical sources
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Annual average per-caput dose (in m
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Military activities 20
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Annual effective dose (mSv) Doses d
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Global average levels Natural sourc
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Annual effective dose (mSv) 6 5 4 3
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Annual per caput dose (mSv) for USA
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(3) Recent Developments on the epis
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26 July, 2012 WNU-Summer Institute
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26 July, 2012 Radiation harm to DNA
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Many other mutations occur due to D
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26 July, 2012 0.5 Mev WNU-Summer I
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26 July, 2012 Chromosomes deletions
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26 July, 2012 Chromosomal aberratio
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26 July, 2012 Probability of mutati
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26 July, 2012 First possible outcom
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26 July, 2012 Cell killingat around
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26 July, 2012 Third possible outcom
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26 July, 2012 Altered process WNU-S
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26 July, 2012 Stochastic effects Ca
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Radiation mutates DNA 26 July, 2012
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26 July, 2012 Radioepidemiology (Ep
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26 July, 2012 Difficult to assess!
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26 July, 2012 The radium dial paint
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26 July, 2012 ..the Mayak cohort of
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…all these victims of radiation e
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Solid Cancer Mortality 47 years of
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26 July, 2012 Hereditable Effects W
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The risk is so low that the estimat
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26 July, 2012 Antenatal Effects WNU
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26 July, 2012 1000mSv = IQ WNU-Summ
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Latest news 89
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Likelihood of health effects 100% (
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Likelihood of health effects 100% (
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26 July, 2012 Take away points WNU-
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Dose Very low dose: about 10 mSv or
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Remember! 1. Radiation exposure at
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Additional information to the FIRST
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Physics and chemistry Biology 10 -1
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New UNSCEAR’s assessments Epidem
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26 July, 2012 Chernobyl workers,
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26 July, 2012 Adaptive Response + M
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The role of apoptosis (cell killing
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26 July, 2012 Genomic instability
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Challenge to the paradigm Mutation
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Bystander effects The so-called “
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26 July, 2012 Signals via intercell
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26 July, 2012 WNU-Summer Institute
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26 July, 2012 Effects in another or
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Does radiation exposure affect the
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(1) The International Organizations
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UNSCEAR 26 July, 2012 WNU-Summer In
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Member States on UNSCEAR Argentina
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ICRP 26 July, 2012 WNU-Summer Insti
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First ICRP meeting 1928 139
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141
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26 July, 2012 The International Ato
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to establish standards IAEA statuto
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International Labour Organisation 1
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(2) The International Radiation Pro
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Total background incidence of effec
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Detriment-adjusted Nominal Risk Coe
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Time Protection basic dogma Shiel
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The principles of radiological prot
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The Principle of Justification •
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adioactive discharges (bad) Is the
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Justification!
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Detriment Detriment +Social cost Op
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Restrictions: Restrictions: dose li
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Source constraint 26 July, 2012 171
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The principle of protection of futu
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D Doses after 1 year of operation 1
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Doses after 3 years of operation D
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Types of exposure situations
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Planned exposure situations, are si
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Emergency exposure situations, •
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Emergency exposure situations Extan
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Doses to be constrained are those c
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Guidance for the protection of pati
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Workers (voluntary and individually
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The female worker: protecting the u
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Members of the Public (involuntary
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Natural background radiation (plann
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- Page 238 and 239: Take away points 1. Additional dose
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agonzale@arn.gob.ar 26 July, 2012 T