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ischaemic preconditioning of the human heart. - Leicester Research ...

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Fizures and Tables<br />

CHAPTERII<br />

Fieures<br />

2,1 Photograph <strong>of</strong> shaking water bath 38<br />

2,2 Experimental protocols for Study 1 40<br />

2.3 A Experimental protocols for Study 2A 40<br />

2.3 B Experimental protocols for Study 2B 41<br />

2A Experimental protocols for Study 3 43<br />

2.5 LDH leakage from right atrial slices in Study 1 58<br />

26 Net LDH leakage from right atnal slices in Study 1 59<br />

2.7 MTT reduction in right atrial slices in Study 1 60<br />

2.8 Myocardial oxygen consumption in right atrial slices in Study 1 60<br />

2.9 Morphological grading 61<br />

2.10 Transmission Electron Micrographs <strong>of</strong> right atnal slices 61<br />

2.11 LDH leakage from right atrial slices in Study 2 62<br />

2.12 MTT reduction in right atfial slices in Study 2 62<br />

2.13 Myocardial oxygen consumption in right atrial slices in Study 2 63<br />

2.14 LDH leakage from right atrial slices in Study 3 64<br />

2.15 MTT reduction in right atfial slices in Study 3 65<br />

Table 2.1 Tissue high energy phosphate contents Appx Ii-I<br />

CHAPTER III<br />

3.1 Experimental protocols for Study 1 71<br />

3.2 Experimental protocols for Study 2 72<br />

3.3 Experimental protocols for Study 3 73<br />

3.4 Experimental protocols for Study 4 74<br />

3.5A &B CK leakage and MTT reduction on <strong>the</strong> effect <strong>of</strong> IP stimulus 84<br />

3.6A &B CK leakage and MTT reduction on <strong>the</strong> effect <strong>of</strong> IP cycles(2min) 85<br />

3.7A &B CK leakage and MTT reduction on <strong>the</strong> effect <strong>of</strong> IP cycles (5min) 86<br />

3.8A &B CK leakage and MTT reduction on <strong>the</strong> effect <strong>of</strong> first window 87<br />

3.9A &B CK leakage and MTT reduction on <strong>the</strong> effect <strong>of</strong> second window<br />

with moderate ischaemia 88<br />

3. IOA &B CK leakage and MTT reduction on <strong>the</strong> effect <strong>of</strong> second window<br />

CHAPTERIV<br />

with severe ischaemia<br />

4.1 Experimental protocols for Study 1 94<br />

4.2 CK leakage and MTT reduction on <strong>the</strong> effect <strong>of</strong> dose-response<br />

experiments on diazoxide 98<br />

4.3 CK leakage and VITT reduction on <strong>the</strong> effect <strong>of</strong> dose-response<br />

experiments on pinacidil<br />

x<br />

89<br />

99

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