ischaemic preconditioning of the human heart. - Leicester Research ...

eduction as described in section 3.2.4 (Chapter 3) and the results expressed as U/g
wet wt and mM/mg wet wt respectively.
7.3 Statistical Analysis
Statistical analyses were carried out using the SPSS 90 statistical package program A
non-parametric test (Mann-Whitney U) was carried out f
-Gaussian d,
or non stfibution
of data. Unpaired Student's t test was used for continuous data (two-tailed) and X2
test for categoric data was used to compare variables between the groups Repeated-
measures analysis of variance (ANOVA) was used to test the repeated observation
variables post -operatl vel y. The area under curve was calculated using the method of
Matthews and Altman [2041. Data was presented as mean f standard deviation (SD)
The level of significance was set at ap value --- Oý05
7.4. Results
7.4.1 In Vivo Studies
There were no operative deaths (first 30 postoperative days) or penoperative
myocardial infarctions in any of the study groups Table 7.1 shows that the patient
characteristics and perioperative data were similar within each study group and that
there was no difference between patients who were treated with or without ischaemic
preconditioning
/- Plasma Troponin T
Figures 7.1 A&B show that the profile of TnT release in plasma was identical in
patients undergoing coronary surgery using CPB whether they were protected using,
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