ischaemic preconditioning of the human heart. - Leicester Research ...
ischaemic preconditioning of the human heart. - Leicester Research ...
ischaemic preconditioning of the human heart. - Leicester Research ...
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Table 7.2 - Patients haemod-v-namic<br />
data.<br />
Variable<br />
Grou V a, -<br />
PS 7<br />
Pre-operative<br />
X-clamn<br />
RCP<br />
HR Mean MAP<br />
(mmHg)<br />
CVP<br />
(mmHg)<br />
Mean PAP<br />
(mmHg)<br />
PCWI'<br />
(mmHg)<br />
(A PVRI SVRI<br />
(L)m2permin) (dvn/%,<br />
--c/cm5, m2)<br />
-PC 68.412.7 71. R+5.7 10.3f-0.8 20.4+1.1 5.8+2.1 2.8+0.2 1(),; + 11 1Wt 102<br />
ýPc 75.8+2.3 69.4+3.5 9.8±2.1 19.4 t 5.2 6.4 13.9 2.4 t 0.4 182 t 20 160203<br />
-PC<br />
59.40.4 65.7f6.9 7.8+5.7 22.616.4 5.1 t 2.6 2.9tO. 4 201 t 13 1497 t 11<br />
, PC 65.1 t 6.8 70.2 12.1 9.1 t 2.4 2 5.1 f 9.3 7.4 t 1.1 1.05to. 19 215! 25 1629! 98<br />
Off-purnp -PC 52.412.9 59.8t8.7 5.6f22 15.9fil. 4 9.3tl. 5 2.52tO. 54 156t12 1307-109<br />
4 Pc 49.50.7 61.4ill. 2 6.7±4.1 21.7t4.8 5.7t2.8 2.74tO. 29 168t25 1567 t 63<br />
I hr post-termination <strong>of</strong> Ischnemia<br />
X<br />
-cýp 10 1.3+<br />
-PC 1.9 65.4t4.7 9.4+12 18.1 t2.7 10.4 t 1.3 2.50 t0 11 217t2O 2(X) I1 52<br />
.<br />
-, - PC 95.6+2.4 59.4+7.2 1 l212.7 22.4 ý- 5.1 8.5-2,1 2. (16*0.28 271,16 1050*11; 7<br />
BCP<br />
Ofl-pumv<br />
-PC<br />
99.8+10.4 71,2+5.9 8.6-0.5 16A+6.9 11.3 t 1.4 2.76 t 0.22 301 t27 2100-554<br />
+ PC 92.7+4.9 64.8 t 6.8 10.2+2.9 21.9+2.4 9.4 t 3.9 2.98+0.15<br />
. 15,7t 12 1 X)3 t 261<br />
-PC<br />
105.5 16.5 7 5.4 t 8.7 11.6 13.9 24.7 19.4 12.1 t 2.6 2.02 t 0.26 298 t 21 1506t23<br />
+ PC 112.2+9.2 77.6±6.2 13.5-0.7 19.7-0.1 10.5 1 1.1 2.43 t 0.18 312 t 12 1709t 141<br />
3 hours post-termination <strong>of</strong> Ischaemin<br />
Vcbn<br />
RCP<br />
()IT-Pqw<br />
-PC<br />
92.4111.5 67.5 15.9 7.7 t 3.2 20.9 t 5.2 11.9 t 6.4<br />
4 PC 84.2+12.7 71.8+11.8 9.2+2.7 19.8 13.4 9.7 t 2.9<br />
-PC<br />
953f 15.1 67.8+11.9 9.8 t 2.4 2 3.7 t 6.8 102 t 1.9<br />
. PC 105.3 124.9 7 7.4 t 4.9 10.7 t 3.1 2 2.7 t 3.6 11.6 t 2.7<br />
-PC<br />
79.5 t 12.9 71.51 12.7 9.4 12.5 21.912.7 8.4 t 2.5<br />
+PC 86.7il4.7 75. lt8.3 7.9t4.2 26.4-t 5.9 9.6 11.6<br />
24 hours post-termination <strong>of</strong> Ischaemia<br />
X -c imp<br />
H(T<br />
()tITYMP<br />
-PC 61.5 t 6.4 62.7 t 2.9 6.4 t: 2.9 19.2 t 2.7 5.8 t 2.3<br />
+ PC 72.9 f 5.8 58.4t9.1 7.6+6.1 16.7t4.9 10.4 f 1.7<br />
-PC 77.9t9.6 61.9t4.6 5.4 t 3.8 21.6 t 5.8 92 t 1.5<br />
+PC 75.4-t 113 71.3+6.1 7.8+1.6 24.9 i 1.1 4.6: 2.8<br />
-PC 91.6-8.7 88.1 f 53 4.410.8 19.6 t 4.6 7.8 t 3.8<br />
ý PC 84.3 t 10.4 90.1 Q. 8 6.8t 1.7 2 3.3 t 3.3 102 t 1.4<br />
2.52 t 0.3 8 250t 17 1954,100<br />
2.2 1t0.2 7 291 ! 67 2304! 328<br />
2.64t0.12 333 t 29 1796 t 447<br />
2.57 t 0.2 5 401 t 46 1667 t 169<br />
2.11 10.15 412 t 29 1509t225<br />
2.92 t 0.26 368t36 1882! 203<br />
2.96 t0 26 208t22 1804t234<br />
2.35 t 0.36 214t50 20N t 102<br />
2.5 5t0.46 289t16 1620198<br />
3. ) 9t0.53 295 t 26 1492.<br />
-207<br />
2.46 t 0.34 312t28 1623t115<br />
2.89t0,41 256 t 33 2 (KM t 204<br />
IICP blood cardioplegia, CI cardiac index, CVP central venous pressure, IIR <strong>heart</strong> rate: MAP mean arterial pressure:<br />
PAP pulmonary artery pressure, PCWII pulmonary capillary wedge prc%sure, PVRI pulnionarN%ascularrt: %i%tiuiceiiide-k.<br />
WRI systemic vascular resistance index. Data are expressed as mean t standard deviation.<br />
157