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Encyclopedia of Drugs, Alcohol, and Addictive Behavior (vol

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INDEX Vol. 1: pp. 1–474; Vol. 2: pp. 475–946<br />

Opioid withdrawal—(Continued)<br />

pharmacotherapy for, 1252–1253<br />

symptoms <strong>of</strong>, 392<br />

Opioids, 227–232, 466–467, 796–801. See<br />

also specific opioids, e.g., Morphine<br />

abuse liability <strong>of</strong>, 241, 989–990<br />

acute effects <strong>of</strong>, 316<br />

addiction to (See Opioid dependence)<br />

aggression <strong>and</strong>, 53, 241<br />

alcohol interactions with, 435<br />

allergic response to, 105<br />

as analgesics (See Opioid analgesics)<br />

animal testing <strong>of</strong>, 986<br />

antagonists for, 1252, 1253<br />

British use <strong>of</strong>, 1009–1010<br />

buprenorphine <strong>and</strong>, 206<br />

caffeine <strong>and</strong>, 210<br />

carbohydrate metabolism <strong>and</strong>, 297<br />

carcinogenicity <strong>of</strong>, 220<br />

chemical structure <strong>of</strong>, 799, 800<br />

clonidine <strong>and</strong>, 261–263<br />

complications from, 801–807<br />

neurological, 334–335<br />

crime <strong>and</strong>, 365–367<br />

cue-assessment studies using, 237<br />

as designer drugs, 383–384<br />

drug interactions <strong>and</strong>, 436<br />

endocrine disorders <strong>and</strong>, 296, 297, 298,<br />

321<br />

endogeneous (See Endogeneous opioids)<br />

enkephalins, 800<br />

epidemics, 491<br />

history <strong>of</strong>, 813–820<br />

iatrogenic addiction to, 619, 620,<br />

621–622<br />

imaging techniques <strong>and</strong>, 625<br />

legislative control <strong>of</strong>, 817–820<br />

for medicinal use, 813–817<br />

memory <strong>and</strong>, 712<br />

narcotics term, 754<br />

neonatal withdrawal <strong>and</strong>, 538–540<br />

peptides <strong>of</strong>, 712, 779, 800<br />

personality <strong>and</strong>, 842<br />

pharmacokinetics <strong>of</strong>, 847<br />

during pregnancy, 892–898<br />

prescribed, for addiction<br />

in Britain, 201–204<br />

receptors for (See Opioid receptors)<br />

reinforcement <strong>and</strong>, 689<br />

Rolleston Committee <strong>and</strong>, 1010–1011<br />

self-administration <strong>of</strong>, 689<br />

subjective effects <strong>of</strong>, 983<br />

tolerance to, 227<br />

treatment for abuse <strong>of</strong> (See Opioid<br />

addiction treatment)<br />

Vietnam War <strong>and</strong>, 1309–1312<br />

withdrawal from (See Opioid withdrawal)<br />

women’s use <strong>of</strong>, 1356<br />

Opium, 820–822, 833, 875–876. See also<br />

Opioids<br />

from Afghanistan, 660–661, 663,<br />

665–666<br />

as antidiarrheal, 681–682, 742, 743,<br />

835–836<br />

Asian use <strong>and</strong> trade <strong>of</strong>, 143–144<br />

carcinogenicity <strong>of</strong>, 220<br />

from China, 253–254, 662–663<br />

codeine from, 272<br />

from Colombia, 284, 655–656, 660–661,<br />

664<br />

crop control <strong>of</strong>, 660<br />

cultivation <strong>of</strong>, 373, 813<br />

in Dover’s powder, 416–417<br />

epidemics, 490<br />

foreign policy <strong>and</strong>, 545–546<br />

from the Golden Crescent, 663<br />

from the Golden Triangle, 660–663<br />

from Guatemala, 655–656, 660–661, 664<br />

Harrison Act <strong>and</strong>, 591–592<br />

heroin from (See Heroin)<br />

from India, 660–661<br />

from Iran, 660–661, 663, 665–666<br />

from Laos, 660–661, 662<br />

from Latin America, 663–664<br />

laudanum from, 681–682<br />

from Lebanon, 660–661<br />

in medications, 417<br />

from Mexico, 660–661, 663–664,<br />

665–666, 725–728<br />

from Middle East, 665–666<br />

from Myanmar, 660–661<br />

from Pakistan, 660–661, 663, 665–666<br />

plant, 821<br />

Terry & Pellens study on, 1082–1083<br />

from Thail<strong>and</strong>, 660–661<br />

Opium Advisory Committee. See League <strong>of</strong><br />

Nations, Opium Advisory<br />

Committee<br />

Opium dens, 816<br />

The Opium Problem, 1083<br />

Opium Wars (1839-1842), 143, 821, 876,<br />

1009<br />

Opportunity blocking <strong>and</strong> drunk driving,<br />

473<br />

Oppositional defiant disorder, 154<br />

Oral contraception, 220, 1103<br />

Oral disorders<br />

alcohol <strong>and</strong>, 220<br />

betel nut mixtures <strong>and</strong>, 184<br />

Oral Health America, 1105<br />

Oral route <strong>of</strong> administration<br />

alcohol concentration times, 860<br />

animal research on, 987, 993<br />

complications from, 340–341<br />

pharmacokinetics <strong>and</strong>, 849, 850<br />

for THC, 1084<br />

Oregon, decriminalization <strong>and</strong>, 701, 838<br />

O’Reilly, Richard T., 839<br />

Orfila Corp., 783–784<br />

Organized crime<br />

in Colombia, 284, 658–660<br />

financial analysis <strong>and</strong>, 443–444<br />

gangs <strong>and</strong>, 566<br />

in Italy, 667<br />

money laundering <strong>and</strong>, 546, 740–741<br />

Prohibition <strong>and</strong>, 935<br />

terrorism <strong>and</strong>, 1080–1082<br />

OSAP. See Center for Substance Abuse<br />

Prevention<br />

O’Shaughnessy, Dr., 593<br />

Osiris (Egyptian deity), 77–78<br />

Osmond, Humphrey, 588, 1024<br />

Osteoporosis <strong>and</strong> alcohol, 338<br />

OTC drugs. See Over-the-counter drugs<br />

OTI. See Office for Treatment Improvement<br />

Outpatient programs, 1216–1217<br />

for cocaine addiction, 1159–1160<br />

group therapy <strong>and</strong>, 1239<br />

vs. inpatient, 1249–1250<br />

Minnesota Model, 1244–1246<br />

nonmethadone, 1220<br />

TOPS study <strong>and</strong>, 1132–1133<br />

Over-the-counter drugs, 823–824, 824<br />

advertising <strong>and</strong>, 42, 43<br />

for alcohol withdrawal, 1342<br />

amphetamines, 115<br />

caffeine in, 210, 211<br />

Dehydroepi<strong>and</strong>rosterone, 124<br />

elderly <strong>and</strong>, 56, 57–60, 61<br />

Overdose, 822, 1247<br />

alcohol-drug interactions <strong>and</strong>, 435<br />

antidotes for, 136–137<br />

1850<br />

<strong>of</strong> barbiturates, 109, 159, 162, 164<br />

<strong>of</strong> benzodiazepines, 1021<br />

<strong>of</strong> caffeine, 213<br />

in children, 248<br />

<strong>of</strong> glutethimide, 579<br />

<strong>of</strong> heroin, 596<br />

in Italy, 669, 670<br />

<strong>of</strong> methanol, 723<br />

<strong>of</strong> nicotine, 784, 1101<br />

<strong>of</strong> opiates, 227<br />

<strong>of</strong> phencyclidine, 866–867, 869<br />

Overeating, 822–823<br />

Overgeneralizing. See Abstinence violation<br />

effect<br />

Own-price elasticity, 167–168<br />

Oxazepam, 172, 173, 177, 178<br />

Oxford House, 68, 90, 1136–1137<br />

Oxidation (Drug metabolism), 446–447<br />

Oxotremorine, 710<br />

Oxycodone, 824, 824–825, 831–832<br />

Oxymetholone, 123, 220<br />

Oxymorphone, 825, 825<br />

vs. naloxone, 751<br />

vs. oxycodone, 824<br />

P. Lorillard, 1094<br />

Pacific Isl<strong>and</strong>s. See also Philippines<br />

alcohol use in, 81<br />

betel nut use in, 182–183<br />

Pagan, Carlos, 1138<br />

Pain, 827–828. See also Chronic pain<br />

acute vs. chronic, 829<br />

analgesics for (See Analgesics)<br />

animal research on, 977<br />

brain stem <strong>and</strong>, 193<br />

drugs for, 828–833, 830, 831 (See also<br />

Analgesics)<br />

iatrogenic addiction <strong>and</strong>, 619–622<br />

morphine for, 828<br />

Painkillers. See Analgesics<br />

Pakistan<br />

crop control in, 375–376<br />

as opium source, 143, 663, 665–666,<br />

1054<br />

tea use in, 1076<br />

Pamelor. See Nortriptyline<br />

Panama, coca paste use in, 264–265<br />

Panax species. See Ginseng<br />

Pancreas<br />

alcohol <strong>and</strong>, 322<br />

glucose metabolism <strong>and</strong>, 297<br />

Panic disorder, 139<br />

benzodiazepines for, 174<br />

LSD-related, 693–694<br />

substance abuse <strong>and</strong>, 329<br />

Papaversomniferum, 833. See also Opium<br />

Papua New Guinea, betel nut use in, 183<br />

PAR (Parental Awareness <strong>and</strong><br />

Responsibility), 1137–1138<br />

Paracelsus, 813–814<br />

Paracrine communication, 777<br />

Paradoxical reactions<br />

to barbiturates, 160, 164<br />

to benzodiazepines, 175, 180<br />

to stimulants, 242<br />

Paraldehyde, 1019<br />

Paranoid personality disorder, 843<br />

Paranoid psychosis<br />

amphetamine-induced, 53, 112<br />

cocaine-induced, 224–225, 265, 270<br />

methamphetamine-induced, 723<br />

methylphenidate-induced, 724–725<br />

Paranoid state <strong>and</strong> alcohol, 293<br />

P

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