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groupe de recherche sur le système nerveux central - GRSNC

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LUND, James P. LUND, James P.Tél. (514) 343-7815 Mé<strong>de</strong>cine <strong>de</strong>ntaire(514) 398-7219 Université <strong>de</strong> MontréalC.P. 6128, Succ. Centre-vil<strong>le</strong>, MontréalFax (514) 343-6113 Canada H3C 3J7(514) 398-8900 URL site WWW:E-Mail: james.lund@mcgill.ca URL personnel CV:Statut universitaire / University statusProfesseur titulaireMé<strong>de</strong>cine <strong>de</strong>ntaireFaculté <strong>de</strong> mé<strong>de</strong>cine <strong>de</strong>ntaireUniversité McGillAppartenance à d'autres <strong>groupe</strong>s / Affiliation with other groupsProfesseur associé, Dép. <strong>de</strong> physiologie, Université <strong>de</strong> MontréalMembre du Groupe <strong>de</strong> <strong>recherche</strong> <strong>sur</strong> <strong>le</strong> système <strong>nerveux</strong> <strong>central</strong> (<strong>GRSNC</strong>) du FRSQFormation / TrainingB.D.S., University of Adélai<strong>de</strong>, 1966Ph.D., University of Western Ontario, Physiologie, 1971Postdoctora<strong>le</strong>, Université <strong>de</strong> Montréal - CRSN, Neurophysiologie, 1971-1973Orientations <strong>de</strong> la <strong>recherche</strong>•Le contrô<strong>le</strong> <strong>de</strong>s mouvements <strong>de</strong> la mâchoire par <strong>de</strong>s circuits <strong>nerveux</strong> du système <strong>central</strong>.•L'effet <strong>de</strong>s afférences sensoriel<strong>le</strong>s, particulièrement <strong>de</strong>s nocicepteurs, <strong>sur</strong> <strong>le</strong> contrô<strong>le</strong> <strong>de</strong>s mouvements.•La dou<strong>le</strong>ur chronique musculosque<strong>le</strong>ttique.•La reconstruction protétique <strong>de</strong>s structures buccofacia<strong>le</strong>s.Principaux projets en cours:•Étu<strong>de</strong> du rô<strong>le</strong> <strong>de</strong>s neurones <strong>de</strong>s noyeux trigeminaux.•Étu<strong>de</strong> <strong>de</strong> l’interaction neuron-glie dans <strong>le</strong> contrô<strong>le</strong> <strong>de</strong> la mastication.•Étu<strong>de</strong> du rô<strong>le</strong> <strong>de</strong>s afférences fusoria<strong>le</strong>s dans la dou<strong>le</strong>ur musculaire chronique.•Étu<strong>de</strong>s comparatives <strong>de</strong> différents types <strong>de</strong> prothèses <strong>de</strong>ntaires supportées par <strong>de</strong>s implants (essais cliniques).Research orientations•The control of movements of mandib<strong>le</strong> by <strong>central</strong> circuits.•The effects of peripheral inputs, particularly pain, on the control of movements.•Chronic musculoske<strong>le</strong>tal pain.•Prosthetic reconstruction of the orofacial structures.Current research projects:•Studies of the ro<strong>le</strong> of neurons in the trigeminal main sensory nuc<strong>le</strong>us in the control of mastication.•Studies of neuronal-glial interactions in the control of mastication.•Studies of the ro<strong>le</strong> of musc<strong>le</strong> spind<strong>le</strong>s in chronic pain.•Comparison of different forms of prostheses supported by <strong>de</strong>ntal implants (clinical trials).Publications choisies/Se<strong>le</strong>cted publicationsVerdier, D., Lund, J.P. and Kolta, A. (2003) GABAergic control of action potential propagation along axonal branches of mammalian sensory neurons. J. Neurosci. 23: 2002-2007.Verdier, D., Lund, J.P. and Kolta, A. (2004) Synaptic inputs to trigeminal primary afferent neurons cause firing and modulate intrinsic oscillatory activity. J. Neurophysiol. 92: 2444-2455.Lund JP and Kolta A. (2006) Brainstem circuits that control mastication: Are they used during speech? J Commun Disord 39: 381-390.Brocard, F, Verdier, D, Arsenault, I, Lund, JP and Kolta, A. (2006) Emergence of intrinsic bursting in trigeminal sensory neurons paral<strong>le</strong>ls the acquisition of mastication inweanling rats.J Neurophysiol. 96: 2410-2424.Lund, J.P. (2008) Persistant Pain and Motor Dysfunction. In: Orofacial Pain: from Basic Science to Clinical Management (2nd edition) Sess<strong>le</strong>, B.J., Lavigne, G.J., Lund, J.P.,and Dubner, R. (Eds.) Quintessence, Chicago, pp 117-124.McDavid, S., Verdier, D., Lund J.P. and Kolta, A. (2008) E<strong>le</strong>ctrical properties of interneurons found within the trigeminal motor nuc<strong>le</strong>us. Eur. J. Neurosci. 28: 1136-1145.Page 52

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