01. Gene therapy Boulikas.pdf - Gene therapy & Molecular Biology

drugs (doxorubicin, cisplatin) but at subtoxic doses and at
much lower concentrations than those used today, as well
as less severe doses of radiation, would become routine
regimens in hospitals for the eradication of all cancer
types. In this respect, the emerging priority in gene
therapy is to improve the efficiency of tissue targeting and
gene delivery.
Acknowledgements
I am grateful to all authors who have kindly provided
their permission and original photos to use in this article.
Special thanks to François Meyer, Max Birnstiel, Brian
Johnston, Marc Vasseur, Claude Hélène, Frank Martin,
Joe Vallner, Douglas Jolly, Jeff Seilhamer, Demetrios
Spandidos, Kaz Taira, Ernst Wagner, Peter Dehlinger, Ko
Kurachi, Dan Maneval, Jerzy Jurkat, Ed Trifonov, and
Emile Zuckerkandl for stimulating discussions. I am also
grateful to past and present members of my group for their
contributions to the ongoing projects related to the
subjects discussed here in particular Linda Hsie, CF Kong,
Dawn Brooks, John Costouros, and Jie Hu, as well as to
my collaborators Maria Zannis-Hadjopoulos, Jürgen Bode,
and Wolfgang Deppert.
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