01. Gene therapy Boulikas.pdf - Gene therapy & Molecular Biology

similarity with functional domains of other viruses. EMBO J
14, 5524-5531.
Raper SE, Grossman M, Rader DJ, Thoene JG, Clark BJ 3rd,
Kolansky DM, Muller DW, Wilson JM (1996) Safety and
feasibility of liver-directed ex vivo gene therapy for
homozygous familial hypercholesterolemia. Ann Surg 223,
116-126.
Raycroft L, Wu H, Lozano G (1990) Transcriptional activation
by wild-type but not transforming mutants of the p53 antioncogene.
Science 249: 1049-1051.
Reddy JC, Hosono S, Licht JD (1995) The transcriptional effect
of WT1 is modulated by choice of expression vector. J Biol
Chem 270, 29976-29982.
Richards CA, Austin EA, and Huber BE (1995) Transcriptional
regulatory sequences of carcinoembryonic antigen:
identification and use with cytosine deaminase for tumorspecific
gene therapy. Hum Gene Ther 6, 881-893.
Richman DD (1996) HIV Therapeutics. Science 272, 1886-1887.
Riley DJ, Nikitin AY, Lee WH (1996) Adenovirus-mediated
retinoblastoma gene therapy suppresses spontaneous
pituitary melanotroph tumors in Rb +/- mice. Nat Med 2,
1316-1321.
Riordan JE, Rommens JM, Kerem B-S, Alon N, Rozmahel R,
Grzelczak Z, Zielenski J, Lok S, Plavsic N, Chou J-L
Drumm MI, Iannuzzi MC, Collins FS, Tsui L-C (1989)
Identification of the cystic fibrosis gene: Cloning and
characterization of complementary DNA. Science 245, 1066-
1073.
Robbins, P.D., Horowitz, J.M. and Mulligan, R.C. (1990)
Negative regulation of human c-fos expression by the
retinoblastoma gene product. Nature 346, 668-671.
Rodolfo M, Zilocchi C, Melani C, Cappetti B, Arioli I, Parmiani
G, Colombo MP (1996) Immunotherapy of experimental
metastases by vaccination with interleukin gene-transduced
adenocarcinoma cells sharing tumor-associated antigens.
Comparison between IL-12 and IL-2 gene-transduced tumor
cell vaccines. J Immunol 157, 5536-5542.
Rodriguez R, Schuur ER, Lim HY, Henderson GA, Simons JW,
Henderson DR(1997) Prostate attenuated replication
competent adenovirus (ARCA) CN706: a selective cytotoxic
for prostate-specific antigen-positive prostate cancer cells.
Cancer Res 57, 2559-2563.
Roessler BJ and Davidson BL (1994) Direct plasmid mediated
transfection of adult murine brain cells in vivo using cationic
liposomes. Neurosci Lett 167, 5-10.
Roessler BJ, Allen ED, Wilson JM, Hartman JW, Davidson BL
(1993) Adenoviral-mediated gene transfer to rabbit
synovium in vivo. J Clin Invest 92, 1085-1092
Rohde M, Warthoe P, Gjetting T, Lukas J, Bartek J, Strauss M
(1996) The retinoblastoma protein modulates expression of
genes coding for diverse classes of proteins including
components of the extracellular matrix. Oncogene 12, 2393-
2401.
Rolling F, Nong Z, Pisvin S, Collen D (1997) Adeno-associated
virus-mediated gene transfer into rat carotid arteries. Gene
Ther 4, 757-761.
Boulikas: An overview on gene therapy
154
Rømer J, Bugge TH, Pyke C, Lund LR, Flick MJ, Degen JL,
Dano K (1996) Impaired wound healing in mice with a
disrupted plasminogen gene. Nat Med 2, 287-292.
Rommerskirch W, Fluharty AL, Peters C, von Figura K,
Gieselmann V (1991) Restoration of arylsulphatase A
activity in human-metachromatic-leucodystrophy fibroblasts
via retroviral-vector-mediated gene transfer. Biochem J 280,
459-461.
Roninson IB, Chin JE, Choi K, Gros P, Housman DE, Fojo A,
Shen D-W, Gottesman MM, Pastan I (1986) Isolation of
human mdr DNA sequencs amplified in multidruf-resistant
KB carcinoma cells. Proc Natl Acad Sci USA 83, 4538-
4542.
Rosenberg SA (1992) The immunotherapy and gene therapy of
cancer. J Clin Oncol 10, 180-199.
Rosenberg SA, Packard BS, Aebersold PM, Solomon D,
Topalian SL, Toy ST, Simon P, Lotze MT, Yang JC, Seipp
CA, Simpson C, Carter C, Bock S, Schwartzentruber D, Wei
JP, and White DE (1988) Use of tumor infiltrating
lymphocytes and interleukin-2 in the immunotherapy of
patients with metastatic melanoma. N Engl J Med 319,
1676-1680.
Rosenberg, SA, Anderson WF, Blaese MR, Ettinghausen SE,
Hwu P, Karp SE, Kasid A, Mule JJ, Parkinson DR, Salo JC,
Schwartzentruber DJ, Topalian Sl, Weber JS, Yannelli JR,
Yang JC, and Linehan WM (1992) Initial proposal of clinical
research project. Immunization of cancer patients using
autologous cancer cells modified by insertion of the gene for
interleukin-2. Hum Gene Ther 3, 75-90.
Rosenecker J, Zhang W, Hong K, Lausier J, Geppetti P,
Yoshihara S, Papahdjopoulos D, Nadel JA (1996) Increased
liposome extravasation in selected tissues: Effect of
substance P. Proc Natl Acad Sci USA 93, 7236-7241.
Rosenfeld MA, Siegfried W, Yoshimura K, Yoneyama K,
Fukayama M, Stier LE, Pääkkö PK, Gilardi P, Stratford-
Perricaudet L, Perricaudet M, Jallat S, Pavirani A, Lecocq J-
P, and Crystal RG (1991) Adenovirus-mediated transfer of
recombinant α1-antitrypsin gene to the lung epithelium in
vivo. Science 252, 431-434.
Rosenfeld MA, Yoshimura K, Trapnell BC, Yoneyama K,
Rosenthal ER, Dalemans W, Fukayama M, Bargon J, Stier
LE, Stratford-Perricaudet L, Perricaudet M, Guggino WB,
Pavirani A, Lecocq J-P, and Crystal RG (1992) In vivo
transfer of the human cystic fibrosis transmembrane
conductance regulator gene to the airway epithelium. Cell
68, 143-155.
Rosenfeld MR, Bergman I, Schramm L, Griffin JA, Kaplitt MG,
Meneses PI (1997) Adeno-associated viral vector gene
transfer into leptomeningeal xenografts. J Neurooncol 34,
139-144.
Rosenfeld MR, Meneses P, Dalmau J, Drobnjak M, Cordon-
Cardo C, Kaplitt MG (1995) Gene transfer of wild-type p53
results in restoration of tumor-suppressor function in a
medulloblastoma cell line. Neurology 45, 1533-1539.
Rosenzweig M, Marks DF, Hempel D, Heusch M, Kraus G,
Wong-Staal F, Johnson RP (1997) Intracellular
immunization of rhesus CD34 + hematopoietic progenitor
cells with a hairpin ribozyme protects T cells and