3. Umbruch 4.4..2005 - Online Pot
3. Umbruch 4.4..2005 - Online Pot
3. Umbruch 4.4..2005 - Online Pot
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Cannabinoids in neurodegeneration and neuroprotection 103<br />
ities of HU-211, a novel NMDA receptor antagonist. Eur J Pharmacol 283: 19–29<br />
38 Hampson AJ, Bornheim LM, Scanziani M, Yost CS, Gray AT, Hansen BM, Leonoudakis DJ,<br />
Bickler PE (1998) Dual effects of anandamide on NMDA receptor-mediated responses and neurotransmission.<br />
J Neurochem 70: 671–676<br />
39 Battaglia G, Bruno V, Pisani A, Centonze D, Catania MV, Calabresi P, Nicoletti F (2001) Selective<br />
blockade of type-1 metabotropic glutamate receptors induces neuroprotection by enhancing<br />
gabaergic transmission. Mol Cell Neurosci 17: 1071–1083<br />
40 Maneuf YP, Nash JE, Croosman AR, Brotchie JM (1996) Activation of the cannabinoid receptor<br />
by D9-THC reduces GABA uptake in the globus pallidus. Eur J Pharmacol 308: 161–164<br />
41 Romero J, de Miguel R, Ramos JA, Fernández-Ruiz J (1998) The activation of cannabinoid receptors<br />
in striatonigral neurons inhibited GABA uptake. Life Sci 62: 351–363<br />
42 Saji M, Blau AD, Volpe BT (1996) Prevention of transneuronal degeneration of neurons in the<br />
substantia nigra reticulata by ablation of the subthalamic nucleus. Exp Neurol 141: 120–129<br />
43 Mackie K, Hille B (1992) Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma<br />
cells. Proc Natl Acad Sci USA 89: 3825–3829<br />
44 Mackie K, Lai Y, Westenbroek R, Mitchell R (1995) Cannabinoids activate an inwardly rectifying<br />
potassium conductance and inhibit Q-type calcium currents in AtT20 cells transfected with rat<br />
brain cannabinoid receptor. J Neurosci 15: 6552–6561<br />
45 Pan X, Ikeda SR, Lewis DL (1996) Rat brain cannabinoid receptor modulates N-type Ca 2+ channels<br />
in a neuronal expression system. Mol Pharmacol 49: 707–714<br />
46 Gebremedhin D, Lange AR, Campbell WB, Hillard CJ, Harder DR (1999) Cannabinoid CB1<br />
receptor of cat cerebral arterial muscle functions to inhibit L-type Ca 2+ channel current. Am J<br />
Physiol Heart Circ Physiol 276: H2085–H2093<br />
47 Chemin J, Monteil A, Perez-Reyes E, Nargeot J, Lory P (2001) Direct inhibition of T-type calcium<br />
channels by the endogenous cannabinoid anandamide. EMBO J 20: 7033–7040<br />
48 Deadwyler SA, Hampson RE, Bennett BA, Edwards TA, Mu J, Pacheco MA, Ward SJ, Childers<br />
SR (1993) Cannabinoids modulate potassium current in cultured hippocampal neurons. Recept<br />
Channel 1: 121–134<br />
49 McAllister SD, Griffin G, Satin LS, Abood ME (1999) Cannabinoid receptors can activate and<br />
inhibit G protein-coupled inwardly rectifying potassium channels in a xenopus oocyte expression<br />
system. J Pharmacol Exp Ther 291: 618–626<br />
50 van der Stelt M, Veldhuis WB, Bar PR, Veldink GA, Vliegenthart JF, Nicolay K (2001)<br />
Neuroprotection by D9-tetrahydrocannabinol, the main active compound in marijuana, against<br />
ouabain-induced in vivo excitotoxicity. J Neurosci 21: 6475–6579<br />
51 Hampson AJ, Grimaldi M (2001) Cannabinoid receptor activation and elevated cyclic AMP reduce<br />
glutamate neurotoxicity. Eur J Neurosci 13: 1529–1536<br />
52 Pong K (2003) Oxidative stress in neurodegenerative diseases: therapeutic implications for superoxide<br />
dismutase mimetics. Expert Opin Biol Ther 3: 127–139<br />
53 Klein JA, Ackerman SL (2003) Oxidative stress, cell cycle, and neurodegeneration. J Clin Invest<br />
111: 785–793<br />
54 Chan PH (2001) Reactive oxygen radicals in signaling and damage in the ischemic brain. J Cereb<br />
Blood Flow Metab 21: 2–14<br />
55 Marsicano G, Moosmann B, Hermann H, Lutz B, Behl C (2002) Neuroprotective properties of<br />
cannabinoids against oxidative stress: role of the cannabinoid receptor CB1. J Neurochem 80:<br />
448–456<br />
56 Hampson AJ, Grimaldi M, Axelrod J, Wink D (1998) Cannabidiol and (–)D9-tetrahydrocannabinol<br />
are neuroprotective antioxidants. Proc Natl Acad Sci USA 95: 8268–8273<br />
57 Chen Y, Buck J (2000) Cannabinoids protect cells from oxidative cell death: a receptor-independent<br />
mechanism. J Pharmacol Exp Ther 293: 807–812<br />
58 Belayev L, Bar-Joseph A, Adamchik J, Biegon A (1995) HU-211, a nonpsychotropic cannabinoid,<br />
improves neurological signs and reduces brain damage after severe forebrain ischemia in rats. Mol<br />
Chem Neuropathol 25: 19–33<br />
59 Braida D, Pegorini S, Arcidiacono MV, Consalez GG, Croci L, Sala M (2003) Post-ischemic treatment<br />
with cannabidiol prevents electroencephalographic flattening, hyperlocomotion and neuronal<br />
injury in gerbils. Neurosci Lett 346: 61–64<br />
60 Malfait AM, Gallily R, Sumariwalla PF, Malik AS, Andreakos E, Mechoulam R, Feldmann M<br />
(2000) The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic<br />
in murine collagen-induced arthritis. Proc Natl Acad Sci USA 97: 9561–9566